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机器人辅助根治性前列腺切除术后第 2 天早期排尿对早期长期控尿的影响:一项随机前瞻性试验。

Superior early and long-term continence following early micturition on day 2 after robot-assisted radical prostatectomy: a randomized prospective trial.

机构信息

Department of Urology, Pediatric Urology and Urologic Oncology, Prostate Center Northwest, St. Antonius Hospital, Moellenweg 22, 48599, Gronau, Germany.

Department of Urology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany.

出版信息

World J Urol. 2021 Mar;39(3):771-777. doi: 10.1007/s00345-020-03225-9. Epub 2020 May 2.

Abstract

PURPOSE

To elucidate early and long-term continence and patient comfort depending on type and duration of catheterization after robot-assisted radical prostatectomy.

METHODS

198 patients were randomized prospectively into three groups (May 2016-July 2017): A transurethral catheter with micturition on postoperative day (POD) 5 was placed in the control group (TD5); a suprapubic tube (SPT) with micturition on POD 5 was placed in the group SD5 or with micturition on POD 2 in group SD2, respectively. Questionnaires were used for catheter-related satisfaction. Functional outcome analysis included residual volume analysis, uroflowmetry, IPSS, 12-h pad test, and daily pad use. Follow-up was conducted up to 12 months.

RESULTS

Postoperative comfort and catheter-related complications were similar in the three groups. However, on the day of catheter removal, continence was significantly better in the 12-h pad test for the SD2 group with 14 ml vs. 30 ml (TD5) and 24 ml (SD5), p = 0.007. Median residual urine volume between the groups was comparable with 17 ml in TD5, 7 ml in SD5, and 11 ml in SD2, (p = 0.07). Postoperative IPSS did not differ significantly in the follow-up period. After 4 weeks, 63% of the patients in SD2 were continent (no pad/day) compared to 33% in TD5 and 41% in SD5, p = 0.004. After 12 months, 76% were continent in TD5, 87% in SD5, and 94% in SD2, p = 0.023.

CONCLUSIONS

Early micturition after SPT placement in robotic radical prostatectomy seems to be beneficial without an increased risk of complications.

摘要

目的

阐明机器人辅助前列腺根治术后根据导管类型和留置时间对早期和长期控尿及患者舒适度的影响。

方法

198 例患者前瞻性随机分为三组(2016 年 5 月至 2017 年 7 月):对照组(TD5)术后第 5 天留置经尿道导尿管排尿;留置耻骨上导管组(SD5)第 5 天排尿或留置耻骨上导管组(SD2)第 2 天排尿。使用问卷评估与导管相关的满意度。功能结局分析包括残余尿量分析、尿流率、IPSS、12 小时尿垫试验和日常尿垫使用。随访时间为 12 个月。

结果

三组患者术后舒适度和导管相关并发症相似。然而,在拔除导尿管当天,SD2 组 12 小时尿垫试验的控尿情况明显更好,其 14ml 与 TD5 组的 30ml(p=0.007)和 SD5 组的 24ml 相比差异有统计学意义。三组间残余尿量中位数无显著差异,TD5 组为 17ml,SD5 组为 7ml,SD2 组为 11ml(p=0.07)。在随访期间,IPSS 无显著差异。4 周后,SD2 组 63%的患者(无垫/天)控尿,而 TD5 组为 33%,SD5 组为 41%,p=0.004。12 个月后,TD5 组 76%、SD5 组 87%和 SD2 组 94%的患者控尿,p=0.023。

结论

机器人辅助前列腺根治术后早期留置耻骨上导管似乎有利于排尿且不增加并发症风险。

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