Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, Germany.
Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC H3T 1C5, Canada.
Curr Oncol. 2021 Nov 15;28(6):4738-4747. doi: 10.3390/curroncol28060399.
To determine the correlation between urine loss in PAD-test after catheter removal, and early urinary continence (UC) in RP treated patients.
Urine loss was measured by using a standardized, validated PAD-test within 24 h after removal of the transurethral catheter, and was grouped as a loss of <1, 1-10, 11-50, and >50 g of urine, respectively. Early UC (median: 3 months) was defined as the usage of no or one safety-pad. Uni- and multivariable logistic regression models tested the correlation between PAD-test results and early UC. Covariates consisted of age, BMI, nerve-sparing approach, prostate volume, and extraprostatic extension of tumor.
From 01/2018 to 03/2021, 100 patients undergoing RP with data available for a PAD-test and early UC were retrospectively identified. Ultimately, 24%, 47%, 15%, and 14% of patients had a loss of urine <1 g, 1-10 g, 11-50 g, and >50 g in PAD-test, respectively. Additionally, 59% of patients reported to be continent. In multivariable logistic regression models, urine loss in PAD-test predicted early UC (OR: 0.21 vs. 0.09 vs. 0.03; for urine loss 1-10 g vs. 11-50 g vs. >50 g, Ref: <1 g; all < 0.05).
Urine loss after catheter removal strongly correlated with early continence as well as a severity in urinary incontinence.
为了确定导管拔除后 PAD 试验中的尿液损失与接受 RP 治疗的患者早期尿控之间的相关性。
在拔除经尿道导管后 24 小时内,使用标准化、经过验证的 PAD 试验测量尿液损失,并将其分为尿液损失<1、1-10、11-50 和>50 克。早期尿控(中位数:3 个月)定义为使用无或一个安全垫。单变量和多变量逻辑回归模型测试了 PAD 试验结果与早期尿控之间的相关性。协变量包括年龄、BMI、神经保留方法、前列腺体积和肿瘤的前列腺外延伸。
2018 年 1 月至 2021 年 3 月,回顾性分析了 100 例接受 RP 且可获得 PAD 试验和早期尿控数据的患者。最终,24%、47%、15%和 14%的患者在 PAD 试验中分别出现<1g、1-10g、11-50g 和>50g 的尿液损失,此外,59%的患者报告有尿控。在多变量逻辑回归模型中,PAD 试验中的尿液损失预测早期尿控(OR:0.21 与 0.09 与 0.03;对于 1-10g 与 11-50g 与>50g 的尿液损失,参考值为<1g;所有 P<0.05)。
导管拔除后尿液损失与早期尿控以及尿失禁的严重程度密切相关。