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心因性非癫痫性发作患者的定量脑电图研究。

Quantitative EEG Findings in Patients With Psychogenic Nonepileptic Seizures.

机构信息

Department of Psychology, 232990Uskudar University, Istanbul, Turkey.

Kemal Arıkan Psychiatry Clinic, Istanbul, Turkey.

出版信息

Clin EEG Neurosci. 2021 May;52(3):175-180. doi: 10.1177/1550059420918756. Epub 2020 May 4.

Abstract

. Psychogenic nonepileptic seizures (PNES), is one of the clinical manifestations of conversion disorder that epileptiform discharges do not accompany. Factors capable of increasing susceptibility to these seizures have not been adequately investigated yet. This study aims to investigate the quantitative electroencephalography (QEEG) findings for PNES by evaluating the resting EEG spectral power changes during the periods between seizures. . Thirty-nine patients (29 females, 10 males) diagnosed with PNES (group 1) and 47 patients (23 females, 24 males) without any psychiatric diagnosis (group 2) were included in the study. The patients underwent a psychiatric examination at their first visit, were diagnosed and their EEGs were recorded. Using fast Fourier transformation (FFT), spectral power analysis was calculated for delta (0.5-4 Hz), theta (4-8 Hz), alpha (8-13 Hz), beta (15-30 Hz), high-beta (25-30 Hz), gamma-1 (31-40 Hz), gamma-2 (41-50 Hz), and gamma (30-80 Hz) frequency bands. . Six separate EEG band power, namely (C3-high beta, C3-gamma, C3-gamma-1, C3-gamma-2, P3-gamma, P3 gamma-1), were found to be higher in the patients diagnosed with PNES than in the control group. . Our findings show that PNES correlate with high-frequency oscillations on central motor and somatosensory cortices.

摘要

精神性非癫痫性发作(PNES)是转换障碍的一种临床表现,不伴有癫痫样放电。能够增加这些发作易感性的因素尚未得到充分研究。本研究旨在通过评估发作间期静息 EEG 谱功率变化来研究 PNES 的定量脑电图(QEEG)发现。

研究纳入了 39 名被诊断为 PNES 的患者(29 名女性,10 名男性,组 1)和 47 名无任何精神科诊断的患者(23 名女性,24 名男性,组 2)。患者在首次就诊时接受了精神病学检查,被诊断并记录了他们的脑电图。使用快速傅里叶变换(FFT),对 delta(0.5-4 Hz)、theta(4-8 Hz)、alpha(8-13 Hz)、beta(15-30 Hz)、high-beta(25-30 Hz)、gamma-1(31-40 Hz)、gamma-2(41-50 Hz)和 gamma(30-80 Hz)频带进行了谱功率分析。

发现 6 个单独的 EEG 频段的功率(C3-high beta、C3-gamma、C3-gamma-1、C3-gamma-2、P3-gamma、P3 gamma-1)在被诊断为 PNES 的患者中高于对照组。

我们的发现表明,PNES 与中央运动和躯体感觉皮质的高频振荡相关。

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