Department of Obstetrics and Gynecology, University Hospital Basel, Spitalstrasse 21, 4056, Basel, Switzerland.
Department of Clinical Research, Statistics and Data Management, University Basel, Schanzenstrasse 55, 4031, Basel, Switzerland.
Arch Gynecol Obstet. 2020 Jun;301(6):1533-1541. doi: 10.1007/s00404-020-05554-x. Epub 2020 May 3.
To prospectively compare the diagnostic accuracy of radial breast ultrasound (r-US) to that of conventional meander-like breast ultrasound (m-US), patients of a consecutive, unselected, mixed collective were examined by both scanning methods.
Out of 1948 dual examinations, 150 revealed suspicious lesions resulting in 168 biopsies taken from 148 patients. Histology confirmed breast cancers in 36 cases. Sensitivity, specificity, accuracy, PPV, and NPV were calculated for r-US and m-US. The examination times were recorded.
For m-US and r-US, sensitivity (both 88.9%), specificity (86.4% versus 89.4%), accuracy (86.9% versus 89.3%), PPV (64.0% versus 69.6%), NPV (both 98.3%), false-negative rate (both 5.6%), and rate of cancer missed by one method (both 5.6%) were similar. The mean examination time for r-US (14.8 min) was significantly (p < 0.01) shorter than for m-US (22.6 min).
Because the diagnostic accuracy of r-US and m-US are comparable, r-US can be considered an alternative to m-US in routine breast US with the added benefit of a significantly shorter examination time.
前瞻性比较径向乳腺超声（r-US）与传统曲折状乳腺超声（m-US）的诊断准确性，连续、非选择性、混合人群的患者接受了两种扫描方法的检查。
在 1948 次双重检查中，有 150 次发现可疑病变，导致对 148 名患者的 168 个活检进行了活检。组织学证实了 36 例乳腺癌。计算了 r-US 和 m-US 的敏感性、特异性、准确性、PPV 和 NPV。记录了检查时间。
对于 m-US 和 r-US，敏感性（均为 88.9%）、特异性（均为 86.4%与 89.4%）、准确性（均为 86.9%与 89.3%）、PPV（64.0%与 69.6%）、NPV（均为 98.3%）、假阴性率（均为 5.6%）和一种方法漏诊的癌症率（均为 5.6%）相似。r-US 的平均检查时间（14.8 分钟）明显（p < 0.01）短于 m-US（22.6 分钟）。
由于 r-US 和 m-US 的诊断准确性相当，因此 r-US 可以替代常规乳腺超声中的 m-US，其额外的优势是检查时间明显缩短。
