Department of Dental Medicine, Division of Orthodontics and Pediatric Dentistry, Karolinska Institutet, Stockholm, Sweden.
Center for Pediatric Oral Health Research, Stockholm, Sweden.
Acta Odontol Scand. 2020 Nov;78(8):565-571. doi: 10.1080/00016357.2020.1756404. Epub 2020 May 4.
To determine the association between maternal age at delivery and caries in offspring.
This registry-based cohort study included all children born between 2000 and 2003 and who were residing in Stockholm County, Sweden, at 7 years of age. Between 2007 and 2010, the cohort ( = 65,259) was examined to determine caries experience (deft scores) at 7 years of age. Age of mother at childbirth was retrieved from the patient histories. Data were analysed using linear regressions.
The lowest mean deft occurred in children born to mothers aged 25-34 years. The final model - adjusted for sex, income, educational level, migration background, family situation, smoking, obesity, small for gestational age, and number of siblings - found that young mothers and older mothers were significant risk indicators for caries experience at 7 years of age.
The present study found a U-shaped relationship between maternal age at childbirth and caries experience in the offspring at age 7 years. The offspring of mothers under 25 or over 34 years of age are at greater risk of having more teeth with caries experience.
探讨产妇分娩年龄与子女龋齿的关系。
本基于登记的队列研究纳入了所有 2000 年至 2003 年期间在瑞典斯德哥尔摩县出生且 7 岁时居住在该县的儿童。2007 年至 2010 年,对该队列( = 65259 人)进行了检查,以确定其 7 岁时的龋齿患病情况(deft 评分)。产妇分娩年龄从病历中获取。采用线性回归进行数据分析。
最低平均 deft 出现在母亲年龄在 25-34 岁的儿童中。最终模型(调整了性别、收入、教育水平、移民背景、家庭状况、吸烟、肥胖、小于胎龄儿和兄弟姐妹数量)发现,年轻母亲和年长母亲是 7 岁儿童龋齿患病的显著风险指标。
本研究发现产妇分娩年龄与 7 岁儿童龋齿患病之间呈 U 形关系。25 岁以下或 34 岁以上产妇的子女发生龋齿的风险更高。