Temple University, Philadelphia, PA, USA.
UC San Diego, La Jolla, CA, USA.
J Empir Res Hum Res Ethics. 2020 Dec;15(5):443-451. doi: 10.1177/1556264620914463. Epub 2020 May 2.
Empirical studies have found that altruism and self-interest are the two primary motivations for enrollment in clinical trials. Some studies have shown that in some cases these two motivations are contingent upon each other, which complicates our understanding of motivation. In this study, we interviewed 27 people with Parkinson's disease about their willingness to enroll in a hypothetical clinical trial. Through inductive, grounded theory analysis of the interview transcripts, we find four different contingent relationships between altruism and self-interest. It is important for ethicists to be aware of these more complex motivations because some are ethically problematic and others not. Moreover, practitioners need to be aware of these contingent relationships so that they can understand the motivations of the research participants.
实证研究发现，利他主义和自身利益是参与临床试验的两个主要动机。一些研究表明，在某些情况下，这两个动机是相互依存的，这使我们对动机的理解变得复杂。在这项研究中，我们采访了 27 名帕金森病患者，了解他们参加假设性临床试验的意愿。通过对访谈记录的归纳、扎根理论分析，我们发现利他主义和自身利益之间存在四种不同的偶然关系。伦理学家意识到这些更为复杂的动机是很重要的，因为其中一些在伦理上有问题，而另一些则没有。此外，从业者需要意识到这些偶然关系，以便他们能够理解研究参与者的动机。
