Çoban Eda, Teker Serap Ruken, Serindağ Helin, Sakalli Nazan, Soysal Aysun
Bakirköy Education and Training Hospital of Neurology, Neurosurgery and Psychiatry, Istanbul, Turkey.
Ideggyogy Sz. 2020 Mar 30;73(3-4):135-139. doi: 10.18071/isz.73.0135.
The syndrome of headache with neurologic deficits and cerebrospinal fluid lymphocytosis (HaNDL) is a rare entity. This disease has been related to migrainous headaches. It is a benign, self-limited disorder, which is characterized by fluctuating neurological symptoms and cerebrospinal fluid lymphocytosis. We describe a case of a 47 years old man with acute onset of headache and aphasia. Cerebrospinal fluid analysis revealed a lymphocytic pleocytosis (25 cells/μl, 100% lymphocytes). Electroencephalogram showed moderate slow rhythm in the left hemisphere, with temporoparietal predominance, and without epileptiform activity. His blood tests as well as magnetic resonance imaging (MRI) results were normal. With the diagnosis of HaNDL syndrome the patient was accepted in the Department of Neurology and discharged with full recovery.
伴有神经功能缺损和脑脊液淋巴细胞增多症的头痛综合征（HaNDL）是一种罕见病症。该疾病与偏头痛性头痛有关。它是一种良性的自限性疾病，其特征为神经症状波动和脑脊液淋巴细胞增多。我们描述了一例47岁男性，急性起病，有头痛和失语症状。脑脊液分析显示淋巴细胞增多（25个细胞/μl，100%为淋巴细胞）。脑电图显示左半球有中度慢节律，以颞顶叶为主，无癫痫样活动。他的血液检查以及磁共振成像（MRI）结果均正常。诊断为HaNDL综合征后，该患者入住神经内科，出院时已完全康复。
