关节活动过度儿童眼前节分析及角膜生物力学特性评估。
Anterior Segment Analysis and Evaluation of Corneal Biomechanical Properties in Children with Joint Hypermobility.
机构信息
University of Health Sciences Kanuni Sultan Süleyman Training and Research Hospital, Clinic of Ophthalmology, İstanbul, Turkey.
University of Health Sciences Gazi Yaşargil Training and Research Hospital, Clinic of Ophthalmology, Diyarbakır, Turkey.
出版信息
Turk J Ophthalmol. 2020 Apr 29;50(2):71-74. doi: 10.4274/tjo.galenos.2019.28000.
OBJECTIVES
To compare anterior segment parameters and biomechanical analysis of the cornea in children with joint hypermobility (JH) and healthy children.
MATERIALS AND METHODS
Cross-sectional case-control study. Fifty eyes of 25 children with JH were compared with 74 eyes of 37 healthy age- and sex-matched controls in terms of refractive, anterior segment topographic, and corneal biomechanical measurements. Axial length (AL) was measured with a Nidek AL-Scan biometry device; corneal-compensated intraocular pressure (IOPcc), Goldmann-correlated IOP (IOPg), corneal hysteresis (CH), and corneal resistance factor (CRF) were measured with a Reichert ocular response analyzer (ORA). Central corneal thickness (CCT), anterior chamber depth (ACD), K1/K2 values, iris diameter, and anterior chamber volume (ACV) were measured with a Sirius topography device.
RESULTS
Mean age in the JH group was 10.56±4.03 years, while that of the control group was 11.27±2.59 years (p=0.23). Spherical equivalent was -0.22±1.02 diopter (D) in the JH group and -0.12±1.12 D in the control group (p=0.60); CCT was 23.01±0.82 µm in the JH group and 23.17±0.82 µm in the control group (p=0.33). There were no significant differences between the two groups in terms of age, sex, IOP, IOPcc, IOPg, CH, CRF, AL, K1, K2, iris diameter, ACD, and ACV.
CONCLUSION
JH, which causes increased flexibility of the joints, was concluded not to cause a significant change in the corneal biomechanical markers of CRF and CH or in anterior segment topographic parameters.
目的
比较关节过度活动症（JH）儿童与健康儿童的眼前节参数和角膜生物力学分析。
材料和方法
这是一项横断面病例对照研究。将 25 名 JH 儿童的 50 只眼与 37 名年龄和性别匹配的健康对照儿童的 74 只眼进行比较，比较内容包括屈光、眼前节地形图和角膜生物力学测量。眼轴（AL）用尼德克 AL-Scan 生物测量仪测量；角膜补偿眼压（IOPcc）、戈德曼相关眼压（IOPg）、角膜滞后（CH）和角膜阻力因子（CRF）用 Reichert 眼反应分析仪（ORA）测量。中央角膜厚度（CCT）、前房深度（ACD）、K1/K2 值、虹膜直径和前房容积（ACV）用 Sirius 地形图仪测量。
结果
JH 组的平均年龄为 10.56±4.03 岁，对照组为 11.27±2.59 岁（p=0.23）。JH 组的等效球镜度数为-0.22±1.02 屈光度（D），对照组为-0.12±1.12 D（p=0.60）；CCT 在 JH 组为 23.01±0.82 µm，在对照组为 23.17±0.82 µm（p=0.33）。两组在年龄、性别、眼压、IOPcc、IOPg、CH、CRF、AL、K1、K2、虹膜直径、ACD 和 ACV 方面均无显著差异。
结论
关节过度活动症导致关节柔韧性增加，但并未导致角膜生物力学标志物 CRF 和 CH 或眼前节参数发生显著变化。
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