Institut Universitaire de Cardiologie et de Pneumologie de Québec-Université Laval, Québec, Québec, Canada.
Faculty of Medicine, Laval University, Québec, Québec, Canada.
Obes Surg. 2020 Aug;30(8):3030-3036. doi: 10.1007/s11695-020-04647-5.
The benefit of exercise training on lipid profile in bariatric surgery patients is scarce. We assess the effect of a supervised exercise-training program on lipid profile following bariatric surgery.
A total of 60 patients were prospectively recruited, of those 49 completed the study (age 41 ± 11 years; body mass index 45.9 ± 6.1 kg/m, 75% women). The bariatric surgery procedures performed were sleeve gastrectomy (SG) (n = 24) and biliopancreatic diversion with duodenal switch (BPD-DS) (n = 25). Of the 49 patients who completed the study, 34 had been randomized to a 12-week supervised exercise training program (exercise group) between the 3rd and the 6th month following bariatric surgery (SG = 17 and BPD-DS = 17). Fasting blood samples and anthropometric measurements were performed preoperatively and at 3, 6, and 12 months after bariatric surgery.
At 6 months and 12 months, percentage of weight loss was similar between groups (6 months: - 29.6 ± 5.5 vs. - 27.8 ± 7.7%; P = 0.371; 12 months: - 38.4 ± 10.4 vs. - 37.9 ± 9.5%; P = 0.876 exercise vs. control). Both groups had an increase in HDL values between the 3nd and the 6th month following bariatric surgery. There was a significantly greater increment in HDL values in the exercise group (0.18 ± 0.14 vs. 0.07 ± 0.12 mmol/L, P = 0.014; exercise vs. control).
Our results showed a beneficial effect of a 12-week supervised exercise-training program in bariatric surgery patients showing similar weight loss on HDL-cholesterol levels without additional effect on LDL-cholesterol levels.
运动训练对减肥手术患者血脂谱的益处尚不清楚。我们评估了监督运动训练计划对减肥手术后血脂谱的影响。
总共招募了 60 名患者，其中 49 名完成了研究（年龄 41 ± 11 岁；体重指数 45.9 ± 6.1 kg/m，75%为女性）。进行的减肥手术程序为胃袖状切除术（SG）（n = 24）和胆胰分流术加十二指肠转位术（BPD-DS）（n = 25）。在完成研究的 49 名患者中，有 34 名被随机分配到减肥手术后第 3 至 6 个月的 12 周监督运动训练计划（运动组）（SG = 17 名，BPD-DS = 17 名）。在减肥手术前和手术后 3、6 和 12 个月进行空腹血样和人体测量测量。
在 6 个月和 12 个月时，两组之间的体重减轻百分比相似（6 个月：-29.6 ± 5.5%对-27.8 ± 7.7%；P = 0.371；12 个月：-38.4 ± 10.4%对-37.9 ± 9.5%；P = 0.876 运动对对照组）。两组在减肥手术后第 3 至 6 个月时 HDL 值均增加。运动组的 HDL 值增加幅度明显更大（0.18 ± 0.14 对 0.07 ± 0.12 mmol/L，P = 0.014；运动对对照组）。
我们的结果表明，12 周监督运动训练计划对减肥手术患者具有有益的效果，可使 HDL-胆固醇水平的体重减轻相似，而对 LDL-胆固醇水平无额外影响。
