Huismans H
Klin Monbl Augenheilkd. 1988 Sep;193(3):304-6. doi: 10.1055/s-2008-1050264.
The author reports on Demodex folliculorum ("hair follicle mite"), a frequent and widespread parasite. These mites are found in hair follicles of eyelashes in particular. In ophthalmology they are responsible for chronic eczematous blepharitis ("blepharitis acarica") with trichiasis and madarosis. Therapy is unsatisfactory. The author has now discovered that isoptocarbachol 3% eyedrops successfully combat Demodex folliculorum. The solution was first tested experimentally on house flies (Musca domestica) and was later used to treat patients affected with the parasite: a cotton bud impregnated with this parasympathomimetic (anticholinesterase) drug was applied to the border of the eyelids several times.
作者报告了毛囊蠕形螨（“毛囊螨”），一种常见且分布广泛的寄生虫。这些螨虫尤其存在于睫毛的毛囊中。在眼科领域，它们会导致伴有倒睫和睫毛脱落的慢性湿疹性睑缘炎（“疥螨性睑缘炎”）。治疗效果并不理想。作者现已发现3%的异氟磷滴眼液能成功对抗毛囊蠕形螨。该溶液首先在家蝇（家蝇属）上进行了实验测试，随后用于治疗感染该寄生虫的患者：将浸有这种拟副交感神经药（抗胆碱酯酶）的棉签多次涂抹于眼睑边缘。
