Nowomiejska Katarzyna, Lukasik Piotr, Brzozowska Agnieszka, Toro Mario Damiano, Sedzikowska Aleksandra, Bartosik Katarzyna, Rejdak Robert
Department of General Ophthalmology, Medical University of Lublin, 20-079 Lublin, Poland.
Department of Ophthalmology, John Paul II Public Hospital in Zamosc, 22-400 Zamosc, Poland.
J Clin Med. 2020 Sep 23;9(10):3069. doi: 10.3390/jcm9103069.
The aim of the study was to analyze the prevalence of ocular demodicosis and ocular surface conditions in patients selected for cataract surgery. Eyelashes from 73 patients selected for cataract surgery were evaluated at × 40 and × 100 magnification using light microscopy. The anterior segment was assessed with the slit lamp. Additionally, Schirmer I and break up time (BUT) tests were carried out before surgery and 1 and 3 months postoperatively. A specially designed questionnaire containing e.g. information about chronic skin and eye diseases, previous ophthalmic surgeries, and patient's hygiene habits was used to assess the demographic variables. A majority of patients were at the age of 70-79 years, and there were more females (83%) in the study group. Demodex folliculorum was found in 48% of the patients. There was a correlation between the number of parasites and the presence of blepharitis, discharge at eyelid margins, and conjunctival hyperemia. Schirmer I and BUT test results were lower in patients with Demodex infestation before and after cataract surgery. The higher number of mites was correlated with lower Schirmer I test results postoperatively. The presence of Demodex mites influences the conjunctiva and lid margins leading to inflammation. The higher number of Demodex mites disturbs the tear film over time after cataract surgery.
本研究的目的是分析接受白内障手术患者的眼部蠕形螨病患病率和眼表状况。使用光学显微镜对73例接受白内障手术患者的睫毛进行40倍和100倍放大评估。使用裂隙灯评估眼前节。此外,在手术前以及术后1个月和3个月进行泪液分泌试验(Schirmer I试验)和泪膜破裂时间(BUT)测试。使用一份专门设计的问卷(包含例如有关慢性皮肤和眼部疾病、既往眼科手术以及患者卫生习惯等信息)来评估人口统计学变量。大多数患者年龄在70 - 79岁之间,研究组中女性更多(83%)。48%的患者发现有毛囊蠕形螨。寄生虫数量与睑缘炎、睑缘分泌物以及结膜充血之间存在相关性。在白内障手术前后,感染蠕形螨的患者的Schirmer I试验和BUT测试结果较低。螨虫数量较多与术后Schirmer I试验结果较低相关。蠕形螨的存在会影响结膜和睑缘,导致炎症。白内障手术后,随着时间推移,蠕形螨数量较多会扰乱泪膜。