Schmid K W, Glaser K, Wykypiel H, Feichtinger H
Pathologisches Institut, Universität Innsbruck, Osterreich.
Klin Wochenschr. 1988 Nov 1;66(21):1093-6. doi: 10.1007/BF01711925.
According to the literature synchronous adenocarcinomas of both, the colon and the gallbladder or the colon and the appendix are extremely unusual. To our knowledge the simultaneous occurrence of all three tumors has never been published before. Preoperative diagnosis of early stage tumors of the gallbladder and the vermiform appendix is also made very seldom. The following case report records an instance of synchronous adenocarcinomas of the gallbladder, the transverse colon, in a colonic polyp and the appendix. Owing to the patient's advanced age simultane cancer occurrence may be mere coincidence. Nevertheless, this extremely rare entity could also be ascribed to a genetic defect or an unknown carcinogenic agent.
据文献记载，结肠与胆囊或结肠与阑尾同时发生腺癌极为罕见。据我们所知，这三种肿瘤同时出现的情况此前从未有过报道。胆囊和阑尾早期肿瘤的术前诊断也非常少见。以下病例报告记录了一例胆囊、横结肠、结肠息肉及阑尾同时发生腺癌的病例。鉴于患者年事已高，同时发生癌症可能纯属巧合。然而，这种极其罕见的情况也可能归因于基因缺陷或某种未知的致癌因素。
