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心内膜和心外膜节律HDx™标测验证了外科迷宫IV型病变模式。

Endocardial and Epicardial Rhythmia HDx™ Mapping Verifies Surgical Cox Maze IV Lesion Pattern.

作者信息

Kharazi Alexandra L, Hernandez Frank Villa, Mounsey J Paul, Kiser Andy C

机构信息

Department of Cardiovascular Sciences, East Carolina University, Greenville, NC, USA.

Cardiovascular Services, St. Clair Hospital, Pittsburgh, PA, USA.

出版信息

J Innov Card Rhythm Manag. 2020 Jan 15;11(1):3969-3974. doi: 10.19102/icrm.2020.110104. eCollection 2020 Jan.

DOI:10.19102/icrm.2020.110104
PMID:32368366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7192144/
Abstract

Atrial fibrillation (AF) remains the most common cardiac dysarrhythmia, with a significant impact on the health-care economy. AF occurs as a result of electrical conduction delays within the atrial tissue, which may stem from fibrosis or other mediators that alter atrial tissue conduction substrate. The Cox maze III and IV procedures block these reentry circuits by directly dividing, or breaking, the self-perpetuating circuit and by isolating these circuits away from the intrinsic cardiac conduction pathway. The Convergent procedure, a hybrid approach to AF ablation, coordinates the electrophysiologist and the cardiac surgeon in a simultaneous or sequential endocardial and epicardial procedure. Because the heart remains electrically active, electroanatomical maps, not anatomical landmarks, guide therapy. However, lesion transmurality and contiguity remain inconsistent. The Rhythmia HDx™ mapping system (Boston Scientific, Natick, MA, USA) offers detailed maps of acute lesion patterns during the ablation procedure. However, these maps require instrumentation and technology found in the electrophysiology laboratory, not in the operating room. We herein present a case during which we performed a Cox maze IV procedure and also applied the Rhythmia HDx™ electroanatomical mapping system (Boston Scientific, Natick, MA, USA) at the time of operation. Through this novel approach, we were able to verify the completeness of the lesions created and reach a procedural endpoint confirmed by both epicardial and endocardial maps of successful electrical isolation of the left atrium posterior wall and pulmonary vein pedicle.

摘要

心房颤动(AF)仍然是最常见的心脏心律失常,对医疗保健经济有重大影响。AF是由于心房组织内的电传导延迟所致,这可能源于纤维化或其他改变心房组织传导基质的介质。Cox迷宫III和IV手术通过直接分割或破坏自我维持的电路,并将这些电路与心脏固有传导途径隔离开来,阻断这些折返电路。Convergent手术是一种用于AF消融的混合方法,它在同步或序贯的心内膜和心外膜手术中协调电生理学家和心脏外科医生。由于心脏仍保持电活动,因此电解剖图而非解剖标志指导治疗。然而,病变的透壁性和连续性仍然不一致。Rhythmia HDx™标测系统(美国马萨诸塞州纳蒂克市波士顿科学公司)可提供消融过程中急性病变模式的详细图谱。然而,这些图谱需要电生理实验室而非手术室中的仪器和技术。我们在此介绍一例在进行Cox迷宫IV手术时同时应用Rhythmia HDx™电解剖标测系统(美国马萨诸塞州纳蒂克市波士顿科学公司)的病例。通过这种新颖的方法,我们能够验证所创建病变的完整性,并达到由心外膜和心内膜图谱证实的手术终点,即成功实现左心房后壁和肺静脉蒂的电隔离。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/ea68024f8cd8/icrm-11-3969-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/a2cd6bec0734/icrm-11-3969-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/bf5a4eba911e/icrm-11-3969-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/39dc823561d1/icrm-11-3969-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/d9c50d33c7b8/icrm-11-3969-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/d0c455f6812f/icrm-11-3969-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/ea68024f8cd8/icrm-11-3969-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/a2cd6bec0734/icrm-11-3969-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/bf5a4eba911e/icrm-11-3969-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/39dc823561d1/icrm-11-3969-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/d9c50d33c7b8/icrm-11-3969-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/d0c455f6812f/icrm-11-3969-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ba5/7192144/ea68024f8cd8/icrm-11-3969-g006.jpg

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本文引用的文献

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Atrial Fibrillation Ablation Guided by a Novel Nonfluoroscopic Navigation System.由新型非荧光透视导航系统引导的心房颤动消融术
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First clinical experience using a novel high-resolution electroanatomical mapping system for left atrial ablation procedures.首次使用新型高分辨率电解剖标测系统进行左心房消融手术的临床经验。
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2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design: a report of the Heart Rhythm Society (HRS) Task Force on Catheter and Surgical Ablation of Atrial Fibrillation. Developed in partnership with the European Heart Rhythm Association (EHRA), a registered branch of the European Society of Cardiology (ESC) and the European Cardiac Arrhythmia Society (ECAS); and in collaboration with the American College of Cardiology (ACC), American Heart Association (AHA), the Asia Pacific Heart Rhythm Society (APHRS), and the Society of Thoracic Surgeons (STS). Endorsed by the governing bodies of the American College of Cardiology Foundation, the American Heart Association, the European Cardiac Arrhythmia Society, the European Heart Rhythm Association, the Society of Thoracic Surgeons, the Asia Pacific Heart Rhythm Society, and the Heart Rhythm Society.
2012年心房颤动导管消融与外科消融专家共识声明:患者选择、手术技术、患者管理与随访、定义、终点及研究试验设计的建议:心律学会(HRS)心房颤动导管消融与外科消融特别工作组报告。与欧洲心脏病学会(ESC)注册分支欧洲心律协会(EHRA)及欧洲心脏心律失常学会(ECAS)合作制定;并与美国心脏病学会(ACC)、美国心脏协会(AHA)、亚太心律学会(APHRS)和胸外科医师学会(STS)协作。得到美国心脏病学会基金会、美国心脏协会、欧洲心脏心律失常学会、欧洲心律协会、胸外科医师学会、亚太心律学会和心律学会管理机构的认可。
Heart Rhythm. 2012 Apr;9(4):632-696.e21. doi: 10.1016/j.hrthm.2011.12.016. Epub 2012 Mar 1.
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Atrial fibrillation: current knowledge and future directions in epidemiology and genomics.心房颤动:流行病学和基因组学的当前知识和未来方向。
Circulation. 2011 Nov 1;124(18):1982-93. doi: 10.1161/CIRCULATIONAHA.111.039677.
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Importance of evaluating conduction block in radiofrequency ablation for atrial fibrillation.评估房颤射频消融中传导阻滞的重要性。
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The multi-purse string maze procedure: a new surgical technique to perform the full maze procedure without atriotomies.多荷包缝线迷宫手术:一种无需心房切开术即可施行完全迷宫手术的新外科技术。
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J Cardiovasc Electrophysiol. 2007 Apr;18(4):358-63. doi: 10.1111/j.1540-8167.2007.00771.x. Epub 2007 Feb 21.
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Surgical ablation as treatment for the elimination of atrial fibrillation: a meta-analysis.手术消融作为消除心房颤动的治疗方法:一项荟萃分析。
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