Ghoreishi Soroush, Zargaran Massoumeh, Baghaei Fahimeh
Faculty of Dentistry, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Heliyon. 2020 Apr 25;6(4):e03848. doi: 10.1016/j.heliyon.2020.e03848. eCollection 2020 Apr.
Biopsy plays a crucial role in definitive diagnosis of lesions and consequently, appropriate treatment of them. Clinicians should correctly do the biopsy in accordance to the existing principles and guidelines to prevent adverse effects on the pathologist's diagnosis. This study aimed to determine the frequency and reasons for not providing definitive histopathological diagnosis of the biopsy samples belong to the laboratory of the Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Hamadan University of Medical Sciences.
Archival reports belong to 2006-2016 period of the related laboratory were studied to determine the reports with no definitive histopathological diagnosis.
Out of 1018 archived reports; 90 reports (8.84%) had no definitive diagnosis. The most common reasons found were incompatibility between the clinical/radiographical diagnosis and histopathological findings for 42 cases (46.66%), absence of adequate information about the clinical/radiographical findings for 17 cases (18.88%) and inappropriate quality of samples for 13 cases (14.44%), respectively.
The reasons for not providing definitive histopathological diagnosis of the biopsy samples in present study indicated that preparation, assessment and diagnosis of microscopic slide by pathologists do not separate from the clinician performance.
活检在病变的明确诊断以及相应的治疗中起着至关重要的作用。临床医生应根据现有的原则和指南正确进行活检,以防止对病理学家的诊断产生不利影响。本研究旨在确定哈马丹医科大学牙科学院口腔颌面病理科实验室活检样本未给出明确组织病理学诊断的频率及原因。
研究该相关实验室2006年至2016年期间的存档报告,以确定未给出明确组织病理学诊断的报告。
在1018份存档报告中,90份报告(8.84%)没有明确诊断。最常见的原因分别是42例(46.66%)临床/影像学诊断与组织病理学结果不相符、17例(18.88%)缺乏关于临床/影像学结果的充分信息以及13例(14.44%)样本质量不合适。
本研究中活检样本未给出明确组织病理学诊断的原因表明病理学家对显微镜载玻片的制备、评估和诊断与临床医生的操作并非相互独立。