Department of Anesthesiology and Pain Medicine, and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Department of Anesthesiology, College of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
J Int Med Res. 2020 May;48(5):300060520922422. doi: 10.1177/0300060520922422.
To assess the impact of irrigating fluid on hemodynamic profiles using real-time non-invasive cardiac output monitoring (NICOM) in elderly patients undergoing monopolar transurethral resection of the prostate (TURP).
Twenty patients between 65 and 80 years of age who were scheduled for monopolar TURP and received spinal anesthesia up to T10 were enrolled. Irrigating fluid (2.7% sorbitol with 0.5% mannitol solution) was used. Hemodynamic profiles including cardiac index, and stroke volume variation (SVV) using NICOM were obtained. Estimated irrigating fluid absorption was indirectly calculated.
The median amount of irrigating fluid used was 6000 mL. The median SVV was 11%, which increased to 12% at 10 minutes after initiating surgery. No significant changes in the cardiac index were observed. The estimated absorption of irrigating fluid was almost zero.
Although the estimated amount of irrigating fluid that was absorbed was negligible, the increase in SVV may indicate intravascular volume depletion with diuresis resulting from mannitol in the irrigating fluid early during irrigation. Therefore, even during short irrigating times, intensive hemodynamic monitoring should be performed to monitor the possibility of intravascular volume depletion as well as volume overload, especially immediately after large amounts of irrigating fluid are used.
使用实时无创心输出量监测(NICOM)评估老年患者行单极经尿道前列腺切除术(TURP)时灌洗液对血流动力学参数的影响。
纳入 20 名年龄在 65 至 80 岁之间、拟行单极 TURP 且接受至 T10 节段脊髓麻醉的患者。使用灌洗液(2.7%山梨醇和 0.5%甘露醇溶液)。使用 NICOM 获取包括心指数和每搏量变异(SVV)在内的血流动力学参数。间接计算估计的灌洗液吸收量。
使用的灌洗液中位数为 6000 mL。SVV 的中位数为 11%,在手术开始后 10 分钟增加至 12%。心指数无明显变化。估计的灌洗液吸收量几乎为零。
尽管吸收的估计灌洗液量可以忽略不计,但 SVV 的增加可能表明在灌洗早期由于灌洗液中的甘露醇导致利尿而出现血管内血容量减少。因此,即使在短时间灌洗期间,也应进行强化血流动力学监测,以监测血管内血容量不足以及容量过载的可能性,尤其是在使用大量灌洗液后。