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生物资源治疗法治疗慢性鼻窦炎和扁桃体炎常见细菌感染的最新综述

An Up-to-Date Review on Bio-Resource Therapeutics Effective against Bacterial Species Frequently Associated with Chronic Sinusitis and Tonsillitis.

机构信息

Department of Plant Physiology, Institute for Biological Research "Sinisa Stankovic" - National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11000 Belgrade, Serbia.

ENT Clinic, Clinical Hospital Centre Zvezdara, Presevska 31, 11000 Belgrade, Serbia.

出版信息

Curr Med Chem. 2020;27(41):6892-6909. doi: 10.2174/0929867327666200505093143.

Abstract

Upper respiratory tract infections include inflammations of the nose, sinuses (sinusitis), pharynx (tonsillitis, pharyngitis) and larynx (laryngitis) with bacteria or viruses as the main cause of these conditions. Due to their repetitive nature, chronic respiratory infections represent a global problem which is often a result of improper treatment. If not treated adequately, these conditions may have serious consequences. On the other hand, mis - and overuse of antibiotics has reduced their efficiency and accelerated the development of resistant bacterial strains, which further complicates the treatment of infections. This literature review will focus on current knowledge regarding medicinal plants and mushrooms which have been traditionally used in the treatment of infections caused by chronic sinusitis and tonsillitis commonly linked to bacteria - Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Fusobacterium nucleatum, Haemophilus influenzae and Moraxella catarrhalis. The present literature overview might be considered as a starting point for the development of novel, natural antimicrobial products with potential practical use in the treatment of chronic tonsillitis and sinusitis.

摘要

上呼吸道感染包括鼻、鼻窦(鼻窦炎)、咽(扁桃体炎、咽炎)和喉(喉炎)的炎症,细菌或病毒是这些疾病的主要病因。由于其反复发作的性质,慢性呼吸道感染是一个全球性问题,通常是由于治疗不当引起的。如果得不到充分治疗,这些疾病可能会产生严重后果。另一方面,抗生素的误用和滥用降低了它们的效率,并加速了耐药细菌菌株的发展,这进一步使感染的治疗变得复杂。本文献综述将重点介绍关于药用植物和蘑菇的现有知识,这些植物和蘑菇在传统上被用于治疗慢性鼻窦炎和扁桃体炎引起的感染,这些感染通常与细菌有关,包括金黄色葡萄球菌、肺炎链球菌、化脓性链球菌、核梭杆菌、流感嗜血杆菌和卡他莫拉菌。本文献综述可被视为开发新型天然抗菌产品的起点,这些产品具有在慢性扁桃体炎和鼻窦炎治疗中实际应用的潜力。

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