镍催化环化策略在吡咯并喹啉、吲哚并喹啉和吲哚并异喹啉合成中的应用。
Nickel-Catalyzed Cyclization Strategy for the Synthesis of Pyrroloquinolines, Indoloquinolines, and Indoloisoquinolines.
机构信息
Department of Organic Chemistry, University of Madras, Guindy Campus, Tamil Nadu, Chennai-600 025, India.
出版信息
Org Lett. 2020 May 15;22(10):3810-3814. doi: 10.1021/acs.orglett.0c01055. Epub 2020 May 5.
PMID:32369374
Abstract
An inexpensive and benchtop stable Ni-catalyst/Zn system for the synthesis of pyrrolo/indoloquinolines and indolo[2,1-]isoquinolines is explored. This platform provides a one-pot entry for the preparation of various pyrrolo and indoloquinolines/isoquinolines, which involves successive C-C and C-N bond formation, respectively. In addition, we have also performed the preliminary photophysical studies for the synthesized compounds.
摘要
探索了一种廉价的、台式稳定的 Ni-催化剂/Zn 体系，用于合成吡咯并/吲哚喹啉和吲哚并[2,1-α]异喹啉。该平台提供了一种一锅法制备各种吡咯并和吲哚喹啉/异喹啉的方法，分别涉及连续的 C-C 和 C-N 键形成。此外，我们还对合成的化合物进行了初步的光物理研究。
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