猫麻疹病毒，一种可能与猫肾疾病相关的新副黏病毒。
Feline Morbillivirus, a New Paramyxovirus Possibly Associated with Feline Kidney Disease.
机构信息
Department of Microbiology, Cornell University, Ithaca, NY 14853, USA.
Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14850, USA.
出版信息
Viruses. 2020 May 1;12(5):501. doi: 10.3390/v12050501.
Feline morbillivirus (FeMV) was first isolated in stray cats in Hong Kong in 2012. Since its discovery, the virus has been reported in domestic cats worldwide, including in Hong Kong, Japan, Italy, US, Brazil, Turkey, UK, Germany, and Malaysia. FeMV is classified in the genus within the family. FeMV research has focused primarily on determining the host range, symptoms, and characteristics of persistent infections in vitro. Importantly, there is a potential association between FeMV infection and feline kidney diseases, such as tubulointerstitial nephritis (TIN) and chronic kidney diseases (CKD), which are known to significantly affect feline health and survival. However, the tropism and viral entry mechanism(s) of FeMV remain unknown. In this review, we summarize the FeMV studies up to date, including the discoveries of various FeMV strains, basic virology, pathogenicity, and disease signs.
猫麻疹病毒（FeMV）于 2012 年在香港的流浪猫中首次分离出来。自发现以来，该病毒已在全球范围内的家猫中报告，包括在香港、日本、意大利、美国、巴西、土耳其、英国、德国和马来西亚。FeMV 分类在 科的 属中。FeMV 的研究主要集中在确定宿主范围、症状和体外持续感染的特征上。重要的是，FeMV 感染与猫的肾脏疾病（如肾小管间质性肾炎（TIN）和慢性肾病（CKD））之间存在潜在的关联，这些疾病已知会严重影响猫的健康和生存。然而，FeMV 的嗜性和病毒进入机制仍不清楚。在这篇综述中，我们总结了迄今为止的 FeMV 研究，包括各种 FeMV 株的发现、基础病毒学、致病性和疾病迹象。
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