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肾移植术后输尿管梗阻及漏的经皮处理

Percutaneous Management of Ureteral Obstructions and Leak After Renal Transplant.

作者信息

Eldem Fatma Gonca, Akıncı Devrim, Çiftçi Türkmen, Ünal Emre, Yıldırım Tolga, Karabulut Erdem, Aki Fazıl Tuncay, Akhan Okan

机构信息

From the Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Exp Clin Transplant. 2021 Aug;19(8):788-798. doi: 10.6002/ect.2019.0422. Epub 2020 Apr 29.

Abstract

OBJECTIVES

The aim of our study was to evaluate the safety and efficacy of percutaneous treatment of ureteral obstructions and leak after renal transplant and to evaluate the long-term results and graft survival rates in a single center.

MATERIALS AND METHODS

This retrospective study included 27 transplant recipients who received percutaneous treatment between January 2000 and December 2010 and who had follow-up data until December 2018. During this period, 294 renal transplants were performed at our institution, with 17 (5.7%) having a ureteral complication. Ten patients included in the study had their transplants at another center. Percutaneous nephrostomy, balloon dilatation, and double J stent placement were used in the management of complications. Cutting balloon dilatation and tandem ureteral stent placement were done in cases of resistant stenosis. Technical success and ureter patency rates were calculated. Graft survival rates were compared between early and late obstruction groups and between successful and unsuccessful interventional treatment.

RESULTS

Among included cases, 21 obstructions (7 early, 13 late) and 8 leaks were detected. The technical success rate of percutaneous nephrostomy was 100% in all groups. The technical success rates of balloon dilatation and double J stent were 100% and 88% in the early and late obstruction groups, respectively. Censored graft survival rates in all groups at 1, 5, and 10 years were 89%, 89%, and 73.9%, respectively. In long-term follow-up, ureter patency rates were 100%, 33%, and 50% for early obstruction, late obstruction, and urinary leak groups, respectively (P = .018). Graft survival rates between early and late obstruction groups were not significantly different. No major complication, allograft loss, or 30-day mortality was seen.

CONCLUSIONS

Percutaneous management of ureteral complications is safe and effective and should be considered as first-line treatment because of its less invasive nature and lower complication and morbidity rates.

摘要

目的

本研究的目的是评估肾移植术后输尿管梗阻及漏的经皮治疗的安全性和有效性,并评估单中心的长期结果和移植物存活率。

材料与方法

这项回顾性研究纳入了2000年1月至2010年12月期间接受经皮治疗且有截至2018年12月随访数据的27例移植受者。在此期间,我们机构共进行了294例肾移植,其中17例(5.7%)出现输尿管并发症。纳入研究的10例患者在其他中心接受了移植。经皮肾造瘘、球囊扩张和双J支架置入用于并发症的处理。对于难治性狭窄,采用切割球囊扩张和串联输尿管支架置入。计算技术成功率和输尿管通畅率。比较早期和晚期梗阻组以及成功和失败的介入治疗组之间的移植物存活率。

结果

在纳入的病例中,检测到21例梗阻(7例早期,13例晚期)和8例漏。所有组经皮肾造瘘的技术成功率均为100%。早期和晚期梗阻组球囊扩张和双J支架的技术成功率分别为100%和88%。所有组1年、5年和10年的截尾移植物存活率分别为89%、89%和73.9%。在长期随访中,早期梗阻、晚期梗阻和尿漏组的输尿管通畅率分别为100%、33%和50%(P = 0.018)。早期和晚期梗阻组之间的移植物存活率无显著差异。未观察到重大并发症、移植肾丢失或30天死亡率。

结论

输尿管并发症的经皮处理安全有效,因其侵入性较小、并发症和发病率较低,应被视为一线治疗方法。

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