Robertson Richard L, Palasis Susan, Rivkin Michael J, Pruthi Sumit, Bartel Twyla B, Desai Nilesh K, Kadom Nadja, Kulkarni Abhaya V, Lam H F Samuel, Maheshwari Mohit, Milla Sarah S, Mirsky David M, Myseros John S, Partap Sonia, Radhakrishnan Rupa, Soares Bruno P, Trout Andrew T, Udayasankar Unni K, Whitehead Matthew T, Karmazyn Boaz
Boston Children's Hospital, Boston, Massachusetts.
Panel Chair, Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia.
J Am Coll Radiol. 2020 May;17(5S):S36-S54. doi: 10.1016/j.jacr.2020.01.036.
Stroke is an uncommon but an important and under-recognized cause of morbidity and mortality in children. Strokes may be due to either brain ischemia or intracranial hemorrhage. Common symptoms of pediatric acute stroke include headache, vomiting, focal weakness, numbness, visual disturbance, seizures, and altered consciousness. Most children presenting with an acute neurologic deficit do not have an acute stroke, but have symptoms due to stroke mimics which include complicated migraine, seizures with postictal paralysis, and Bell palsy. Because of frequency of stroke mimics, in children and the common lack of specificity in symptoms, the diagnosis of a true stroke may be delayed. There are a relatively large number of potential causes of stroke mimic and true stroke. Consequently, imaging plays a critical role in the assessment of children with possible stroke and especially in children who present with acute onset of stroke symptoms. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
中风在儿童中虽不常见,但却是导致发病和死亡的一个重要且未得到充分认识的原因。中风可能是由于脑缺血或颅内出血引起的。小儿急性中风的常见症状包括头痛、呕吐、局部无力、麻木、视觉障碍、癫痫发作和意识改变。大多数出现急性神经功能缺损的儿童并非患有急性中风,而是因类似中风的症状所致,这些症状包括复杂性偏头痛、发作后瘫痪的癫痫发作以及贝尔麻痹。由于儿童中类似中风症状的发生率较高,且症状通常缺乏特异性,真正中风的诊断可能会延迟。导致类似中风和真正中风的潜在原因相对较多。因此,影像学检查在评估可能患有中风的儿童,尤其是那些出现急性中风症状的儿童时起着关键作用。美国放射学会适宜性标准是针对特定临床情况的循证指南,每年由多学科专家小组进行审查。指南的制定和修订包括对同行评审期刊上当前医学文献的广泛分析,以及应用成熟的方法(兰德/加州大学洛杉矶分校适宜性方法和推荐评估、制定与评价分级或GRADE)来评估特定临床场景下影像学检查和治疗程序的适宜性。在缺乏证据或证据不明确的情况下,专家意见可能会补充现有证据以推荐影像学检查或治疗。