绝经后妇女常规补钙的有效性和安全性。叙述性综述。
Effectiveness and safety of routine calcium supplementation in postmenopausal women. A narrative review.
机构信息
Mobility Impairment Research Center, Babol University of Medical Sciences, Babol, Iran; Clinical Research Developmemt Unit, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Department of Biostatic and Epidemiology, Babol University of Medical Sciences, Babol, Iran.
出版信息
Diabetes Metab Syndr. 2020 Jul-Aug;14(4):435-442. doi: 10.1016/j.dsx.2020.04.016. Epub 2020 Apr 22.
BACKGROUND
To determine whether routine administration of calcium supplementation is useful in postmenopausal women, while it is associated with an increased risk of cardiovascular complications.
METHODS
A literature search was performed using Medline/PubMed, Scopus and Google Scholar by using relevant keywords.
RESULTS
Calcium supplement exerts a small protective effect against bone loss which disappears after cessation. Antifracture effect of supplemental calcium is limited to older frail women or community-dwelling residents who are vitamin D deficient and have inadequate dietary calcium intake. The results of studies on the association between calcium supplementation and cardiovascular complications are contradictory and do not lead to a decisive conclusion CONCLUSION: Current data do not support routine calcium supplementation to all postmenopausal women for prevention of bone loss or bone fracture.
背景
为了确定在绝经后妇女中常规补充钙是否有益，而补充钙又与心血管并发症风险增加有关。
方法
使用相关关键字在 Medline/PubMed、Scopus 和 Google Scholar 上进行文献检索。
结果
钙补充剂对骨质流失有轻微的保护作用，但停止补充后这种作用就消失了。补充钙的抗骨折作用仅限于维生素 D 缺乏且饮食中钙摄入不足的年老体弱妇女或社区居住者。关于钙补充与心血管并发症之间关联的研究结果相互矛盾，无法得出明确的结论。
结论
目前的数据不支持所有绝经后妇女常规补充钙以预防骨质流失或骨折。
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