Division of Cardiothoracic Anesthesiology, Department of Anesthesiology, Virginia Commonwealth University, Richmond, Virginia, USA.
Division of Cardiothoracic Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Curr Opin Anaesthesiol. 2020 Jun;33(3):463-474. doi: 10.1097/ACO.0000000000000858.
The present review examines how targeted approaches to care, based on individual variability in patient characteristics, could be applied in the perioperative setting. Such an approach would enhance individualized risk assessment and allow for targeted preventive and therapeutic decision-making in patients at increased risk for adverse perioperative events.
Prior and current studies highlight valuable lessons on how future investigations attempting to link specific patient-related characteristics or treatment modalities with outcomes and adverse drug responses might be designed in the perioperative setting.
Our review highlights the past, present, and future directions of perioperative precision medicine. Current evidence provides important lessons on how a specific patient and disease tailored approach can help perioperative physicians in delivering the most appropriate and safest perioperative care.
本综述探讨了如何在围手术期基于患者特征的个体差异，采用有针对性的护理方法。这种方法可以增强个体化风险评估，并允许对高风险不良围手术期事件的患者进行有针对性的预防和治疗决策。
先前和当前的研究强调了在围手术期尝试将特定的患者相关特征或治疗方式与结局和药物不良反应相关联时，未来的研究应该如何设计的宝贵经验。
本综述强调了围手术期精准医学的过去、现在和未来方向。现有证据提供了重要的经验教训，即如何采用特定的患者和疾病个体化方法，帮助围手术期医生提供最合适和最安全的围手术期护理。
