Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Chem Commun (Camb). 2020 Jun 11;56(46):6241-6244. doi: 10.1039/d0cc02550j. Epub 2020 May 6.
The three component hydroxyletherification and hydroxylazidation reactions of (trifluoromethyl)alkenes are reported, providing various useful α-trifluoromethyl β-heteroatom substituted tertiary alcohols in high yields. The ipso-defluorooxylation of (trifluoromethyl)alkenes with oximes is completely inhibited. A pesticidal active compound could be synthesized with our method.
报告了（三氟甲基）烯烃的三组分羟乙醚化和羟氮杂化反应，以高产率提供了各种有用的α-三氟甲基β-杂原子取代的叔醇。肟对（三氟甲基）烯烃的邻位去氟氧化完全被抑制。我们的方法可以合成一种具有农药活性的化合物。
