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使用水作溶剂催化氧化醇和胺制备高附加值化学品。

Catalytic Oxidation of Alcohols and Amines to Value-Added Chemicals using Water as the Solvent.

机构信息

Department of Chemistry, Indian Institute of Technology, Delhi Hauz Khas, New Delhi, 110016, India.

出版信息

Chem Asian J. 2020 Jul 1;15(13):1916-1936. doi: 10.1002/asia.202000299. Epub 2020 May 27.

Abstract

Designing reactions in aqueous media has been one of the major challenges in modern organic synthesis, especially to avoid the use of large amounts of organic solvents whose disposal is a matter of grave concern from an environmental perspective. The oxidation of alcohols and amines is an essential and important step in the synthesis of many valuable products including polymers and pharmaceuticals. In recent times, there has been a surge in the use of water as a solvent in many organic reactions. This review focuses specifically on the oxidation reactions of alcohols and amines carried out in water media using transition metal catalysts, metal-free catalysts and photocatalysts.

摘要

在水相介质中设计反应一直是现代有机合成的主要挑战之一,特别是要避免使用大量有机溶剂,因为从环境角度来看,处理这些有机溶剂是一个严重关切的问题。醇和胺的氧化是许多有价值产品(包括聚合物和药物)合成中的一个重要步骤。近年来,在许多有机反应中,水作为溶剂的使用呈激增趋势。本综述专门关注使用过渡金属催化剂、无金属催化剂和光催化剂在水介质中进行的醇和胺的氧化反应。

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