Department of Clinical Medical Nutrition, University Hospital Graz, 8036 Graz, Austria.
Department of Nutritional Sciences, RF Molecular Nutritional Science, University Vienna, 1090 Vienna, Austria.
Nutrients. 2020 May 3;12(5):1306. doi: 10.3390/nu12051306.
Malnutrition in liver cirrhosis is frequently underestimated. To determine if a patient is at risk of malnutrition, several screening tools have been established. However, most of them are not validated for patients with liver cirrhosis. Therefore, we compared the RFH-NPT (Royal Free Hospital Nutritional Prioritizing Tool) as the validated gold standard for malnutrition screening in cirrhosis patients with GMS (Graz Malnutrition Screening), NRS-2002 (Nutritional Risk Screening) and MNA-SF (Mini Nutritional Assessment-Short Form). Based on common validity criteria for screening tools, only the MNA-SF showed fair correlation (12/15 points) with the RFH-NPT, whereas NRS-2002 and GMS performed worse (6/15 points). Taken together, our results suggest that NRS-2002 and GMS are not suitable for screening of malnutrition in cirrhosis patients. A cirrhosis-specific screening tool like RFH-NPT should be used to assess malnutrition and to identify those at risk of malnutrition.
肝硬化患者常存在营养不良被低估的情况。为了确定患者是否存在营养不良风险，已经建立了几种筛选工具。然而，它们大多数都没有针对肝硬化患者进行验证。因此，我们比较了 RFH-NPT（皇家自由医院营养优先工具）作为肝硬化患者营养不良筛选的验证金标准，与 GMS（格拉茨营养不良筛选）、NRS-2002（营养风险筛选）和 MNA-SF（迷你营养评估-短表）的应用。根据筛选工具的共同有效性标准，只有 MNA-SF 与 RFH-NPT 显示出良好的相关性（12/15 分），而 NRS-2002 和 GMS 的相关性较差（6/15 分）。综上所述，我们的结果表明，NRS-2002 和 GMS 不适合用于肝硬化患者的营养不良筛选。应使用像 RFH-NPT 这样的肝硬化特异性筛选工具来评估营养不良，并识别那些有营养不良风险的患者。
