Voigt C, Saeger W, Gerigk C, Lüdecke D K
Department of Pathology, Marienkrankenhaus Hamburg, FRG.
Pathol Res Pract. 1988 Sep;183(5):555-7. doi: 10.1016/S0344-0338(88)80008-6.
71 surgically removed pituitary adenomas with amyloid deposits were studied by light microscopical and immunohistological means. In none of the adenomas was there a predominance of amyloid deposits. There were no correlations between the extent or pattern of the deposits with either age, immunohistological hormone content or localization. Our results do not support either of the theories about the origin of amyloid--whether mesenchymal or produced by adenoma cells--in pituitary adenomas.
对71例手术切除的伴有淀粉样沉积物的垂体腺瘤进行了光学显微镜和免疫组织学研究。在所有腺瘤中,均未发现淀粉样沉积物占优势的情况。沉积物的范围或模式与年龄、免疫组织学激素含量或定位之间均无相关性。我们的结果不支持关于垂体腺瘤中淀粉样物质起源的两种理论——无论是间充质起源还是由腺瘤细胞产生。