二氢吡啶并-1,3,4-三氮杂卓酮衍生物的合成及初步药理学研究
Synthesis and preliminary pharmacological studies on dihydropyrido-1,3,4-triazepinone derivatives.
作者信息
Nawojski A, Liszkiewicz H, Nawrocka W, Wilimowski M, Barczyńska J, Kedzierska L, Wojewódzki W, Rutkowska M, Duś E, Szelag A
机构信息
Department of Technology of Drugs, Medical Academy, Wroclaw, Poland.
出版信息
Pol J Pharmacol Pharm. 1988 Jan-Feb;40(1):63-71.
PMID:3237560
Abstract
New 4,5-dihydropyrido-[2,3-e]-1,3,4-triazepin-5-one derivatives (2-9) were synthesized. The preliminary pharmacological tests revealed antinociceptive action of compounds 4-7 and 9 and antianxiety action of compound 4.
摘要
合成了新型4,5-二氢吡啶并-[2,3-e]-1,3,4-三氮杂卓-5-酮衍生物（2-9）。初步药理试验显示化合物4-7和9具有抗伤害感受作用，化合物4具有抗焦虑作用。
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