Taheri Parsa, Khajeh-Amiri Alireza
Toxicology Research Center, Aja University of Medical Sciences, Tehran, Iran.
Toxicology Research Center, Aja University of Medical Sciences, Tehran, Iran.
Int J Biol Macromol. 2020 May 3;158:282-289. doi: 10.1016/j.ijbiomac.2020.04.258.
Development of chitosan nanofiber (CNF)/nano‑silver phosphate (AgPO) coatings is reported for the fabrication of antibacterial cotton fabrics. The surface morphology and chemical composition were evaluated by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS), respectively. SEM results revealed that AgPO have formed micron-scale clusters and were not completely deposited on the fabric's surface whereas CNFs properly coated the fabric. However, once the hybrid of CNFs and AgPO was utilized, nanoparticles were better deposited on the fabric. The porous and nano-fibrous structure of CNFs provided an ideal substrate to which nanoparticles tightly adhered. The antibacterial activity of the as-synthesized AgPO nanoparticles was demonstrated by measuring the minimum inhibitory concentration (MIC). Moreover, the antibacterial property of the coated fabrics was demonstrated by colony counting method and zone of inhibition (ZOI). The bacterial adhesion reductions for CNF/AgPO coated fabrics were obtained as 100 and 99.8% against S. aureus and E. coli, respectively. Moreover, ZOI was highly increased in the case of the hybrid coating. The results demonstrated the promising potential of CNF/AgPO coatings for the fabrication of antibacterial cotton fabrics to be used as antibacterial garments for clinical environments.
据报道，壳聚糖纳米纤维（CNF）/纳米磷酸银（AgPO）涂层用于制备抗菌棉织物。分别通过扫描电子显微镜（SEM）和X射线光电子能谱（XPS）对表面形态和化学成分进行了评估。SEM结果显示，AgPO形成了微米级的聚集体，并未完全沉积在织物表面，而CNFs则很好地包覆了织物。然而，一旦使用CNFs和AgPO的混合物，纳米颗粒就能更好地沉积在织物上。CNFs的多孔和纳米纤维结构为纳米颗粒紧密附着提供了理想的基质。通过测量最低抑菌浓度（MIC）证明了合成的AgPO纳米颗粒的抗菌活性。此外，通过菌落计数法和抑菌圈（ZOI）证明了涂层织物的抗菌性能。CNF/AgPO涂层织物对金黄色葡萄球菌和大肠杆菌的细菌粘附减少率分别为100%和99.8%。此外，混合涂层的抑菌圈显著增大。结果表明，CNF/AgPO涂层在制备用于临床环境的抗菌服装的抗菌棉织物方面具有广阔的应用前景。
