Dudina T V
Probl Endokrinol (Mosk). 1988 Nov-Dec;34(6):59-62.
Studies on receptor binding of 3H-corticosterone in different brain structures of mature Wistar rats after a single x-irradiation at a dose of 12.9 mCoul/kg, short-term vertical vibration, glucocorticoid application, and surgical adrenalectomy showed a high sensitivity of all studied structures to the body level of glucocorticoids. Any of these influences caused redistribution of receptor binding of 3H-corticosterone in all brain structures, with a marked effect in the parietal cortex and mediobasal hypothalamus, which characterized the central mechanisms of regulation of the pituitary-adrenal system under extreme influences.
对成熟Wistar大鼠单次以12.9毫库仑/千克剂量进行X射线照射、短期垂直振动、应用糖皮质激素以及进行肾上腺切除术之后，对其不同脑结构中³H-皮质酮的受体结合情况进行的研究表明，所有研究结构对糖皮质激素的机体水平均具有高度敏感性。这些影响中的任何一种都会导致³H-皮质酮在所有脑结构中的受体结合发生重新分布，在顶叶皮质和下丘脑中间基底部有显著作用，这表征了在极端影响下垂体-肾上腺系统调节的中枢机制。
