Kılıç Mustafa, Erçalık Tülay
Department of Neurosurgery, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Department of Physical Medicine and Rehabilitation, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Sisli Etfal Hastan Tip Bul. 2019 Jul 8;53(2):148-153. doi: 10.14744/SEMB.2018.50480. eCollection 2019.
The aim of the present study was to investigate the effect of previous spinal surgery on intradiscal ozone-oxygen (O-O) treatment in low back pain associated with lumbar disc herniation (LDH).
Patients who underwent intradiscal O-O therapy for LDH-induced low back pain were screened retrospectively from hospital records. To ensure homogenization of participants, patients who had received O-O therapy to L4-L5 and L5-S1 intervertebral discs, those with pre-injection and post-injection month 1 data, and those who completed the first year of treatment were included in the study. Patients who completed the first year of treatment but with missing data were contacted and followed up by phone. Patients who underwent surgery at the same level as the injection level were classified as Group 1 (n=30), and those without surgery were classified as Group 2 (n=43). Pain and disability were measured by Visual Analog Scale (VAS) and Oswestry Disability Index (ODI), respectively.
There was no statistically significant difference between the pre-injection VAS and ODI scores of the groups (p=0.719 and p=0.108). Group 1 had significantly higher VAS and ODI scores on month 1 and year 1 than Group 2, and statistically significant decreases were seen in VAS and ODI scores in both groups at follow-up (p<0.001 for all). There was no statistically significant difference between month 1 and year 1 VAS evaluations of the groups with respect to ≥50% improvement in pain reduction (p=0.213 and p=0.347).
In the present study, the effect of the history of spinal surgery on intradiscal O-O treatment results was investigated. Intradiscal injection was found to be effective for both groups, but more successful results were obtained in patients without surgical history.
本研究旨在探讨既往脊柱手术对椎间盘臭氧 - 氧气(O - O)治疗腰椎间盘突出症(LDH)所致腰痛的影响。
从医院记录中回顾性筛选接受椎间盘O - O治疗LDH所致腰痛的患者。为确保参与者的同质性,纳入接受L4 - L5和L5 - S1椎间盘O - O治疗的患者、有注射前和注射后第1个月数据的患者以及完成第一年治疗的患者。对完成第一年治疗但数据缺失的患者通过电话进行联系和随访。在注射水平相同部位接受手术的患者分为第1组(n = 30),未接受手术的患者分为第2组(n = 43)。分别采用视觉模拟评分法(VAS)和Oswestry功能障碍指数(ODI)测量疼痛和功能障碍。
两组注射前VAS和ODI评分无统计学显著差异(p = 0.719和p = 0.108)。第1组在第1个月和第1年的VAS和ODI评分显著高于第2组,两组随访时VAS和ODI评分均有统计学显著下降(所有p < 0.001)。两组在第1个月和第1年VAS评估中,疼痛减轻≥50%方面无统计学显著差异(p = 0.213和p = 0.347)。
本研究调查了脊柱手术史对椎间盘O - O治疗结果的影响。发现椎间盘注射对两组均有效,但无手术史的患者取得了更成功的结果。