Çoban Eda
Department of Neurology, Bakirkoy Mental and Neurological Diseases Training and Research Hospital, Istanbul, Turkey.
Sisli Etfal Hastan Tip Bul. 2019 Aug 28;53(3):272-275. doi: 10.14744/SEMB.2018.81994. eCollection 2019.
Malnutrition is frequently observed in patients with acute stroke and its prevalence after stroke varies widely among published reports. Differences in the timing of assessment, stroke type, comorbid medical conditions, and stroke complications may have contributed to this large variability. This study is conducted to investigate the prevalence of malnutrition, and its associated risk factors in stroke patients admitted to our stroke clinic.
A prospective design was used to measure the nutritional status and nutritional risk of stroke patients during hospitalisation between June 2016 and February 2017. Nutritional status was measured at admission. Demographic data and information on clinical variables were collected, which included the patient's age, gender, type of stroke and other comorbid disorders. Blood samples, including concentrations of high-sensitivity C-reactive protein (CRP), serum albumin, serum creatinine, lipid profile and serum lymphocyte count, were measured by routine methods. Nutritional status was measured using the Mini Nutritional Assessment (MNA); for elderly stroke patients (age older than 65). For stroke patients younger than 65 age, Nutrition Screening 2002 (NRS 2002) was used.
318 patients with acute stroke were assessed for their nutritional status at admission. There were 145 (45%) female and 173 (55%) male patients. Their mean age was 66.16±14.32. 66.1% of the patients elder than 65 years were malnourished. 12.2% of the patients younger than 65 years were found to be malnourished. We found no relationship between comorbidities and malnutrition, except hyperlipidemia. Nourished stroke patients older than 65 years had higher serum lipid levels than the malnourished patients. We also found no relationship between malnutrition biomarkers and being malnourished.
Malnutrition is frequently observed in patients with stroke. Early recognition of malnutrition is crucial, but the absence of valid markers hampers to find out the presence of malnutrition. Thus, further research is needed in targeting the modifiable nutrition risk factors and give attention to nutrition in stroke patients.
急性脑卒中患者中经常出现营养不良,且卒中后其患病率在已发表的报告中差异很大。评估时间、卒中类型、合并的内科疾病以及卒中并发症的差异可能导致了这种巨大的变异性。本研究旨在调查入住我院卒中门诊的卒中患者中营养不良的患病率及其相关危险因素。
采用前瞻性设计来测量2016年6月至2017年2月住院期间卒中患者的营养状况和营养风险。入院时测量营养状况。收集人口统计学数据和临床变量信息,包括患者的年龄、性别、卒中类型和其他合并症。通过常规方法检测血样,包括高敏C反应蛋白(CRP)、血清白蛋白、血清肌酐、血脂谱和血清淋巴细胞计数。使用微型营养评定法(MNA)测量营养状况;用于老年卒中患者(年龄大于65岁)。对于年龄小于65岁的卒中患者,使用2002年营养筛查(NRS 2002)。
318例急性卒中患者在入院时接受了营养状况评估。有145例(45%)女性和173例(55%)男性患者。他们的平均年龄为66.16±14.32岁。66.1%的65岁以上患者营养不良。发现12.2%的65岁以下患者营养不良。除高脂血症外,我们未发现合并症与营养不良之间存在关联。65岁以上营养良好的卒中患者血清脂质水平高于营养不良患者。我们也未发现营养不良生物标志物与营养不良之间存在关联。
卒中患者中经常观察到营养不良。早期识别营养不良至关重要,但缺乏有效的标志物阻碍了对营养不良存在情况的发现。因此,需要进一步研究针对可改变的营养风险因素,并关注卒中患者的营养状况。