平衡：身体活动对西班牙裔美国 2 型糖尿病患者糖尿病教育效果的贡献。
En Balance: The Contribution of Physical Activity to the Efficacy of Spanish Diabetes Education of Hispanic Americans with Type 2 Diabetes.
机构信息
Center for Health Disparities and Molecular Medicine, Loma Linda University School of Medicine, 11085 Campus Street, Loma Linda, CA 92350, USA.
University of California San Diego, School of Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, 9500 Gilman Drive, La Jolla, CA 92093, USA.
出版信息
J Diabetes Res. 2020 Apr 19;2020:4826704. doi: 10.1155/2020/4826704. eCollection 2020.
PURPOSE
, a culturally sensitive diabetes education program, improves glycemic control in Hispanics with type 2 diabetes. The program emphasized diet, physical activity, and other factors important for glycemic control. However, the individual contributions of these education factors are unclear. The purpose of this study is to assess the contribution of physical activity to the success of in improving the health of Mexican Americans with type 2 diabetes.
METHODS
A retrospective study was conducted with plasma samples collected pre- and post-3-month study. Samples from 58 (18 males and 40 females) Hispanic subjects with type 2 diabetes were analyzed for the concentration of kynurenines, known to decrease in response to exercise. After three months, health outcomes for the active group (decreased kynurenines) and the rest of the cohort were evaluated by paired Wilcoxon signed-rank test.
RESULTS
Half of the subjects had increased kynurenine levels at the end of the educational program. We found that the subjects in the active group with decreased kynurenine concentrations displayed statistically greater improvements in fasting blood glucose, A1C, cholesterol, and triglycerides despite weight loss being higher in the group with increased kynurenine concentrations.
CONCLUSIONS
participants with decreased kynurenine levels had significantly improved glycemic control. These data suggest that physical activity significantly contributes to the success of the education program. This analysis indicates that diabetes public health educators should emphasize the benefit of physical activity on glycemic control even in the absence of major weight loss.
目的
是一种文化敏感型糖尿病教育计划，可改善 2 型糖尿病西班牙裔患者的血糖控制。该计划强调饮食、体育活动和其他对血糖控制很重要的因素。然而，这些教育因素的个体贡献尚不清楚。本研究的目的是评估体育活动对 成功改善 2 型糖尿病墨西哥裔美国人健康状况的贡献。
方法
进行了一项回顾性研究，采集了 3 个月研究前后的血浆样本。分析了 58 名（18 名男性和 40 名女性）2 型糖尿病西班牙裔受试者的样本，以确定犬尿酸的浓度，已知犬尿酸会因运动而降低。三个月后，通过配对 Wilcoxon 符号秩检验评估积极组（犬尿酸降低）和其余队列的健康结果。
结果
一半的受试者在教育计划结束时犬尿酸水平升高。我们发现，尽管犬尿酸浓度增加组的体重减轻更多，但犬尿酸浓度降低组的空腹血糖、A1C、胆固醇和甘油三酯的改善具有统计学意义。
结论
犬尿酸水平降低的参与者血糖控制显著改善。这些数据表明，体育活动对 的教育计划的成功有显著贡献。该分析表明，即使没有明显的体重减轻，糖尿病公共卫生教育者也应该强调体育活动对血糖控制的益处。
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