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En Balance 西班牙语糖尿病教育计划改善了西班牙裔糖尿病患者的载脂蛋白、血清葡萄糖和身体成分。

The En Balance Spanish diabetes education program improves apolipoproteins, serum glucose and body composition in Hispanic diabetics.

机构信息

Loma Linda University School of Public Health, Loma Linda, California 92350, USA.

出版信息

Ethn Dis. 2012 Spring;22(2):215-20.

Abstract

OBJECTIVE

We evaluated the changes in apolipoproteins, glycemic status, and body composition after 3 months using a culturally sensitive diabetes education program, En Balance, in diabetic Hispanics.

METHODS

Thirty-four (9 males, 25 females) Hispanic diabetics participated in the En Balance program over three months. Body composition was determined by dual energy X-ray absorptiometry (DXA), fasting plasma glucose (FPG), A1c, and apolipoproteins (Apo) measured after 3 months participation. Differences were analyzed using paired t testing and relationships between changes in Apo, A1c, total cholesterol, body mass index and body composition by Spearman correlations.

RESULTS

Completion of En Balance resulted in a significant reduction in weight (80.31 +/- 1.97 kg vs 81.25 +/- 17.97 kg, P = .015), FPG (143.21 +/- 57.8 mg/dL vs 166.41 +/- 65.9 mg/dL P = .003), and A1c (7.08 +/- 1.6% vs 7.87 +/- 2.0%, P = < .001). DXA demonstrated reduction in total fat (29.54 +/- 10.0 kg vs 30.24 +/- 11.80 kg, P = < .001) and trunk fat (15.09 +/- 5.6 kg vs 16.87 +/- 5.4 kg, P = .001). High density lipoprotein significantly increased (48.85 +/- 11.4 vs 44.65 +/- 8.8, P = .002) and total serum cholesterol/high density lipoprotein ratio decreased (3.87 +/- .98 vs 4.35 +/- 1.0, P = .001). There were significant correlations at three months between changes in Apo A1 and A2 (r = .559, P < .001), Apo E and total cholesterol (r = .746, P < .001), between A1c and FPG (r = .563, P = .001) and BMI and body weight (r = .732, P < .001).

CONCLUSIONS

The En Balance program improved body composition, A1c, FPG, total cholesterol/HDL ratio and HDL. If these trends can be sustained, En Balance may serve as a unique educational paradigm for improving type 2 diabetes in Hispanics.

摘要

目的

通过三个月的文化敏感型糖尿病教育计划“En Balance”,评估糖尿病西班牙裔人群的载脂蛋白、血糖状态和身体成分的变化。

方法

34 名(9 名男性,25 名女性)西班牙裔糖尿病患者参加了“En Balance”计划三个月。使用双能 X 射线吸收法(DXA)测定身体成分,空腹血糖(FPG)、A1c 和载脂蛋白(Apo)在三个月后测定。采用配对 t 检验分析差异,采用 Spearman 相关性分析 Apo、A1c、总胆固醇、体重指数和身体成分变化之间的关系。

结果

完成“En Balance”计划后,体重(80.31 ± 1.97 kg 比 81.25 ± 17.97 kg,P =.015)、FPG(143.21 ± 57.8 mg/dL 比 166.41 ± 65.9 mg/dL,P =.003)和 A1c(7.08 ± 1.6% 比 7.87 ± 2.0%,P = <.001)显著降低。DXA 显示总脂肪(29.54 ± 10.0 kg 比 30.24 ± 11.80 kg,P = <.001)和躯干脂肪(15.09 ± 5.6 kg 比 16.87 ± 5.4 kg,P =.001)减少。高密度脂蛋白显著增加(48.85 ± 11.4 比 44.65 ± 8.8,P =.002),总胆固醇/高密度脂蛋白比值降低(3.87 ±.98 比 4.35 ± 1.0,P =.001)。三个月时,Apo A1 和 A2(r =.559,P <.001)、Apo E 和总胆固醇(r =.746,P <.001)之间,A1c 和 FPG(r =.563,P =.001)以及 BMI 和体重(r =.732,P <.001)之间存在显著相关性。

结论

“En Balance”计划改善了身体成分、A1c、FPG、总胆固醇/高密度脂蛋白比值和高密度脂蛋白。如果这些趋势能够持续下去,“En Balance”可能成为改善西班牙裔 2 型糖尿病的独特教育模式。

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