Loma Linda University School of Public Health, Loma Linda, California 92350, USA.
Ethn Dis. 2012 Spring;22(2):215-20.
We evaluated the changes in apolipoproteins, glycemic status, and body composition after 3 months using a culturally sensitive diabetes education program, En Balance, in diabetic Hispanics.
Thirty-four (9 males, 25 females) Hispanic diabetics participated in the En Balance program over three months. Body composition was determined by dual energy X-ray absorptiometry (DXA), fasting plasma glucose (FPG), A1c, and apolipoproteins (Apo) measured after 3 months participation. Differences were analyzed using paired t testing and relationships between changes in Apo, A1c, total cholesterol, body mass index and body composition by Spearman correlations.
Completion of En Balance resulted in a significant reduction in weight (80.31 +/- 1.97 kg vs 81.25 +/- 17.97 kg, P = .015), FPG (143.21 +/- 57.8 mg/dL vs 166.41 +/- 65.9 mg/dL P = .003), and A1c (7.08 +/- 1.6% vs 7.87 +/- 2.0%, P = < .001). DXA demonstrated reduction in total fat (29.54 +/- 10.0 kg vs 30.24 +/- 11.80 kg, P = < .001) and trunk fat (15.09 +/- 5.6 kg vs 16.87 +/- 5.4 kg, P = .001). High density lipoprotein significantly increased (48.85 +/- 11.4 vs 44.65 +/- 8.8, P = .002) and total serum cholesterol/high density lipoprotein ratio decreased (3.87 +/- .98 vs 4.35 +/- 1.0, P = .001). There were significant correlations at three months between changes in Apo A1 and A2 (r = .559, P < .001), Apo E and total cholesterol (r = .746, P < .001), between A1c and FPG (r = .563, P = .001) and BMI and body weight (r = .732, P < .001).
The En Balance program improved body composition, A1c, FPG, total cholesterol/HDL ratio and HDL. If these trends can be sustained, En Balance may serve as a unique educational paradigm for improving type 2 diabetes in Hispanics.
通过三个月的文化敏感型糖尿病教育计划“En Balance”，评估糖尿病西班牙裔人群的载脂蛋白、血糖状态和身体成分的变化。
34 名（9 名男性，25 名女性）西班牙裔糖尿病患者参加了“En Balance”计划三个月。使用双能 X 射线吸收法（DXA）测定身体成分，空腹血糖（FPG）、A1c 和载脂蛋白（Apo）在三个月后测定。采用配对 t 检验分析差异，采用 Spearman 相关性分析 Apo、A1c、总胆固醇、体重指数和身体成分变化之间的关系。
完成“En Balance”计划后，体重（80.31 ± 1.97 kg 比 81.25 ± 17.97 kg，P =.015）、FPG（143.21 ± 57.8 mg/dL 比 166.41 ± 65.9 mg/dL，P =.003）和 A1c（7.08 ± 1.6% 比 7.87 ± 2.0%，P = <.001）显著降低。DXA 显示总脂肪（29.54 ± 10.0 kg 比 30.24 ± 11.80 kg，P = <.001）和躯干脂肪（15.09 ± 5.6 kg 比 16.87 ± 5.4 kg，P =.001）减少。高密度脂蛋白显著增加（48.85 ± 11.4 比 44.65 ± 8.8，P =.002），总胆固醇/高密度脂蛋白比值降低（3.87 ±.98 比 4.35 ± 1.0，P =.001）。三个月时，Apo A1 和 A2（r =.559，P <.001）、Apo E 和总胆固醇（r =.746，P <.001）之间，A1c 和 FPG（r =.563，P =.001）以及 BMI 和体重（r =.732，P <.001）之间存在显著相关性。
“En Balance”计划改善了身体成分、A1c、FPG、总胆固醇/高密度脂蛋白比值和高密度脂蛋白。如果这些趋势能够持续下去，“En Balance”可能成为改善西班牙裔 2 型糖尿病的独特教育模式。
