戈瓦皂苷 B，一种来自. 根茎的新甾体皂苷。

Govanoside B, a new steroidal saponin from rhizomes of .

机构信息

Natural Product Chemistry and Process Development Division and AcSIR, CSIR-Institute of Himalayan Bioresource Technology, Palampur, India.

出版信息

Nat Prod Res. 2022 Jan;36(1):37-45. doi: 10.1080/14786419.2020.1761360. Epub 2020 May 6.

DOI:10.1080/14786419.2020.1761360

PMID:32378425

Abstract

, commonly known as Nag Chhatri and Teen Patra, is a popular herbal supplement traditionally used for curing different inflammatory and sexual disorders, infection and wound healing. Steroidal saponins are considered as active components of this species. The present study demonstrated the isolation of nine steroidal saponins, including one new compound named as govanoside B () and eight known, pregna-chacotrioside (), pennogenin-triglycoside (), borassoside E (), pennogenin-tetraglycoside (), protodioscin (), clintonioside B (), pennogenin-diglycoside () and borassoside D (). This is the first report on the isolation of , , , , , and from rhizomes of . The extract, fractions and isolated compounds were further evaluated for their DPPH and ABTS radical scavenging activity.

摘要

，俗称 Nag Chhatri 和 Teen Patra，是一种传统的草药补充剂，用于治疗各种炎症和性障碍、感染和伤口愈合。甾体皂苷被认为是该物种的活性成分。本研究从块茎中分离得到了 9 种甾体皂苷，包括一种新化合物命名为 govanoside B () 和 8 种已知化合物，pregna-chacotrioside ()、pennogenin-triglycoside ()、borassoside E ()、pennogenin-tetraglycoside ()、protodioscin ()、clintonioside B ()、pennogenin-diglycoside () 和 borassoside D ()。这是首次从根茎中分离得到、、、、、和。提取物、馏分和分离得到的化合物进一步评估了它们对 DPPH 和 ABTS 自由基清除活性。