阴道和阴道外细菌定植与女性细菌性阴道病发病风险：一项男男性行为人群研究
Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men.
机构信息
Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
University of Washington, Seattle, Washington, USA.
出版信息
J Infect Dis. 2022 Apr 1;225(7):1261-1265. doi: 10.1093/infdis/jiaa233.
BACKGROUND
Bacterial vaginosis (BV) is a common cause of vaginal discharge and associated with vaginal acquisition of BV-associated bacteria (BVAB).
METHODS
We used quantitative polymerase chain reaction assays to determine whether presence or concentrations of BVAB in the mouth, anus, vagina, or labia before BV predict risk of incident BV in 72 women who have sex with men.
RESULTS
Baseline vaginal and extra-vaginal colonization with Gardnerella spp, Megasphaera spp, Sneathia spp, BVAB-2, Dialister sp type 2, and other BVAB was more common among subjects with incident BV.
CONCLUSIONS
Prior colonization with BVAB is a consistent risk for BV.
背景
细菌性阴道病（BV）是阴道分泌物增多的常见原因，与阴道内 BV 相关细菌（BVAB）的获得有关。
方法
我们使用定量聚合酶链反应检测来确定 72 名与男性发生性行为的女性在发生 BV 之前口腔、肛门、阴道或阴唇中是否存在或存在多少 BVAB，以及它们是否会预测 BV 的发生风险。
结果
基线时阴道和阴道外的阴道加德纳菌、巨球形菌、小链菌、BVAB-2、迪氏杆菌 2 型和其他 BVAB 定植与发生 BV 的受试者更为常见。
结论
BVAB 的定植是发生 BV 的一个持续风险因素。
Zotero 插件