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心血管系统与2019冠状病毒病:来自一个发展中国家的视角

Cardiovascular system and COVID-19: perspectives from a developing country.

作者信息

Kunal Shekhar, Gupta Kashish, Sharma Shashi Mohan, Pathak Vijay, Mittal Shruti, Tarke Chandrakant

机构信息

Department of Cardiology, Sawai Man Singh Medical College, Jaipur.

Department of Medicine, Sawai Man Singh Medical College, Jaipur.

出版信息

Monaldi Arch Chest Dis. 2020 May 7;90(2). doi: 10.4081/monaldi.2020.1305.

DOI:10.4081/monaldi.2020.1305
PMID:32380802
Abstract

A novel coronavirus, SARS-CoV-2, thought to have originated from bats causes COVID-19 infection which was first reported from Wuhan, China in December 2019. This virus has a high infectivity rate and has impacted a significant chunk of the population worldwide. The spectrum of disease ranges from mild to severe with respiratory system being the most commonly affected. Cardiovascular system often gets involved in later stages of the disease with acute cardiac injury, heart failure and arrhythmias being the common complications. In addition, the presence of cardiovascular co-morbidities such as hypertension, coronary artery disease in these patients are often associated with poor prognosis. It is still not clear regarding the exact mechanism explaining cardiovascular system involvement in COVID-19. Multiple theories have been put forward however, more robust studies are required to fully elucidate the "heart and virus" link. The disease has already made its presence felt on the global stage and its impact in the developing countries is going to be profound. These nations not only have a poorly developed healthcare system but there is also a huge burden of cardiovascular diseases. As a result, COVID-19 would adversely impact the already overburdened healthcare network leading to impaired cardiovascular care delivery especially for acute coronary syndrome and heart failure patients.

摘要

一种新型冠状病毒,即严重急性呼吸综合征冠状病毒2(SARS-CoV-2),据信起源于蝙蝠,可引发2019冠状病毒病(COVID-19)感染,该病于2019年12月在中国武汉首次报告。这种病毒具有很高的感染率,已影响到全球相当一部分人口。疾病谱从轻度到重度不等,呼吸系统是最常受影响的部位。心血管系统常在疾病后期受累,常见并发症包括急性心脏损伤、心力衰竭和心律失常。此外,这些患者中存在高血压、冠状动脉疾病等心血管合并症往往与预后不良有关。目前仍不清楚解释心血管系统在COVID-19中受累的确切机制。虽然已经提出了多种理论,但仍需要更有力的研究来充分阐明“心脏与病毒”之间的联系。这种疾病已经在全球舞台上崭露头角,其对发展中国家的影响将是深远的。这些国家不仅医疗保健系统欠发达,而且心血管疾病负担也很重。因此,COVID-19将对本已不堪重负的医疗网络产生不利影响,导致心血管护理服务受损,尤其是对急性冠状动脉综合征和心力衰竭患者。

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