Paludetti G, Todisco T, Fedeli L, Giombini E, Rosignoli M, Almadori G
Dept. of O.R.L., University of Perugia, Italy.
Rhinology. 1988 Dec;26(4):257-62.
In 13 healthy young adults, nasal mucociliary transport velocity was measured by means of albumine microsphere labeled with Tc99m as a tracer. M + ISD of clearance velocity values and of the half time radioactivity (T1/2) resulted to be respectively 1.02 + 0.22 cm/min and 1.07 + 0.24 min. A significant correlation (P less than 0.05) between half time clearance (T1/2) values of the radioactive particles and the mucociliary velocity ones could be detected, making T1/2 a reliable and rapidly obtainable parameter for determining nasal mucociliary function. Advantages and disadvantages of the different techniques are discussed.
在13名健康的年轻成年人中，以用99m锝标记的白蛋白微球作为示踪剂，测量鼻黏膜纤毛运输速度。清除速度值和放射性半衰期（T1/2）的平均值±标准差分别为1.02±0.22厘米/分钟和1.07±0.24分钟。可检测到放射性颗粒的半衰期清除（T1/2）值与黏膜纤毛速度值之间存在显著相关性（P<0.05），这使得T1/2成为用于确定鼻黏膜纤毛功能的可靠且可快速获得的参数。文中讨论了不同技术的优缺点。
