Yapıcıer Özlem, Nanah Abdel Rahman, Taskapılıoglu Mevlüt Özgür, Demir Mustafa Kemal
Department of Pathology, Bahçeşehir University School of Medicine, Göztepe Medical Park Training and Education Hospital, Istanbul, Turkey.
Bahçeşehir University School of Medicine, Istanbul, Turkey.
Childs Nerv Syst. 2021 Feb;37(2):649-657. doi: 10.1007/s00381-020-04652-0. Epub 2020 May 8.
Mesenchymal chondrosarcoma is a rare high-grade malignant subtype of chondrosarcoma that is characterized by undifferentiated, round, or spindled mesenchymal cells, interspersed with islands of hyaline cartilage. We report a primary intracranial extra-axial mesenchymal chondrosarcoma in a 16-month-old patient with a review of the literature focusing on intracranial extra-axial MCs with or without skull involvement in pediatric patients, including differential diagnosis. The patient was admitted with a swelling in the right temporooccipital region. There was intracranial extra-dural extension of the mass, which abuts the neural parenchyma without any invasion. A complete tumor resection was performed. Pathological diagnosis was mesenchymal chondrosarcoma. The patient was free of symptoms after surgery.
间叶性软骨肉瘤是软骨肉瘤中一种罕见的高级别恶性亚型，其特征是未分化的圆形或梭形间叶细胞，散在分布于透明软骨岛之间。我们报告了一名16个月大的原发性颅内轴外间叶性软骨肉瘤患者，并对文献进行了综述，重点关注儿科患者中有无颅骨受累的颅内轴外间叶性软骨肉瘤，包括鉴别诊断。该患者因右颞枕部肿胀入院。肿块有颅内硬膜外扩展，紧邻神经实质但无任何侵犯。进行了肿瘤全切术。病理诊断为间叶性软骨肉瘤。患者术后无症状。
