Paule B, Quillard J, Bennet P, Bisson M, Massias P
Service de Rhumatologie, Hôpital de Bicêtre, Le-Kremlin-Bicêtre.
Rev Rhum Mal Osteoartic. 1988 Dec;55(12):969-72.
The degree of medullary infiltration by plasmocytes has a prognostic value which completes the clinical classifications proposed in multiple myeloma. Beyond a 50 p. cent medullary infiltration, the mean survival of the patients is significantly shorter (p less than 0.02) than survival of patients presenting less than 50 p. cent medullary infiltration. The degree of medullary infiltration is unrelated to the stage of Durie and Salmon classification, but is correlated to the degree of differentiation of the plasmocytes.
浆细胞的髓质浸润程度具有预后价值，这完善了多发性骨髓瘤中提出的临床分类。髓质浸润超过50%时，患者的平均生存期明显短于（p<0.02）髓质浸润低于50%的患者。髓质浸润程度与Durie和Salmon分期无关，但与浆细胞的分化程度相关。
