Department of Pediatric Dentistry, Universidade Federal de Santa Catarina - UFSC, Florianopolis, Brazil.
Department of Pediatric Dentistry and Orthodontics, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, Brazil.
Community Dent Oral Epidemiol. 2020 Aug;48(4):257-263. doi: 10.1111/cdoe.12535. Epub 2020 May 7.
The aim of this systematic review and meta-analysis was to determine the impact of dental pain on oral health-related quality of life (OHRQoL) in children and adolescents.
Electronic and manual searches were performed with no restrictions of language or year of publication. The PECO strategy was used to identify observational studies involving participants up to 19 years of age with dental pain and to those without dental pain to determine the impact of this condition on OHRQoL. The methodological quality of the studies was appraised using the Fowkes and Fulton checklist. Meta-analysis was conducted by subgroups, based on OHRQoL questionnaires and effect measures. The quality of evidence was evaluated using the GRADE approach.
Sixteen studies were included in the systematic review and fourteen in the meta-analysis. The methodological quality of four of these studies was considered poor. The pooled results of the subgroup analysis (SOHO-5, B-ECOHIS and Child-OIDP) showed that children with dental pain had a 3.64-fold greater chance of a negative impact on OHRQoL ([log] 95% CI: 2.80-4.72; I 0%; P < .001). The second meta-analysis (Child-OIDP, SOHO-5 and CPQ8-10) demonstrated statistical significance (SMD 0.79; 95% CI: 0.43-1.16; I 92%; P < .001), as did the pooled results considering the B-ECOHIS ([log] OR 7.75; 95% CI: 4.59-13.11; I 84%; P < .001). The certainty of evidence in all meta-analyses was low.
Although the quality of the evidence is low, dental pain has a negative impact on OHRQoL.
本系统评价和荟萃分析的目的是确定儿童和青少年的牙痛对口腔健康相关生活质量（OHRQoL）的影响。
无语言或出版年限限制地进行电子和手动搜索。使用 PECO 策略来确定涉及有牙痛和无牙痛的参与者的观察性研究，以确定这种情况对 OHRQoL 的影响。使用 Fowkes 和 Fulton 清单评估研究的方法学质量。根据 OHRQoL 问卷和效应度量，进行亚组荟萃分析。使用 GRADE 方法评估证据质量。
系统评价纳入了 16 项研究，荟萃分析纳入了 14 项研究。其中四项研究的方法学质量被认为较差。亚组分析（SOHO-5、B-ECOHIS 和 Child-OIDP）的汇总结果表明，有牙痛的儿童对 OHRQoL 产生负面影响的可能性增加了 3.64 倍（[log] 95%CI：2.80-4.72；I 0%；P<.001）。第二次荟萃分析（Child-OIDP、SOHO-5 和 CPQ8-10）也显示了统计学意义（SMD 0.79；95%CI：0.43-1.16；I 92%；P<.001），考虑到 B-ECOHIS 的汇总结果也是如此（[log] OR 7.75；95%CI：4.59-13.11；I 84%；P<.001）。所有荟萃分析的证据确定性都很低。
尽管证据质量较低，但牙痛对 OHRQoL 有负面影响。
