Department of Obstetrics, Gynecology, & Reproductive Sciences, the Divisions of Critical Care Medicine and Obstetric Anesthesia, Department of Anesthesia and Perioperative Care, the Divisions of Pediatric Infectious Diseases and Neonatology, Department of Pediatrics, the Division of Infectious Diseases, Department of Medicine, and the Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Francisco, San Francisco, California.
Obstet Gynecol. 2020 Jul;136(1):46-51. doi: 10.1097/AOG.0000000000003949.
Data suggest that pregnant women are not at elevated risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or developing severe disease compared with nonpregnant patients. However, management of pregnant patients who are critically ill with coronavirus disease 2019 (COVID-19) infection is complicated by physiologic changes and other pregnancy considerations and requires balancing maternal and fetal well-being.
We report the case of a patient at 28 weeks of gestation with acute respiratory distress syndrome (ARDS) from COVID-19 infection, whose deteriorating respiratory condition prompted delivery. Our patient's oxygenation and respiratory mechanics improved within hours of delivery, though she required prolonged mechanical ventilation until postpartum day 10. Neonatal swabs for SARS-CoV-2 and COVID-19 immunoglobulin (Ig) G and IgM were negative.
We describe our multidisciplinary management of a preterm pregnant patient with ARDS from COVID-19 infection and her neonate.
数据表明，与非孕妇患者相比，孕妇感染严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）或发展为重症疾病的风险并未增加。然而，患有 2019 冠状病毒病（COVID-19）感染的危重孕妇的管理因生理变化和其他妊娠因素而变得复杂，需要平衡母婴的健康。
我们报告了一例妊娠 28 周的 COVID-19 感染所致急性呼吸窘迫综合征（ARDS）患者，其呼吸状况恶化促使分娩。我们的患者在分娩后数小时内氧合和呼吸力学得到改善，但她需要长时间的机械通气，直到产后第 10 天。新生儿 SARS-CoV-2 拭子和 COVID-19 免疫球蛋白（Ig）G 和 IgM 均为阴性。
我们描述了我们对一名患有 COVID-19 感染所致 ARDS 的早产孕妇及其新生儿的多学科管理。
