Jeganathan Kristine, Paul Anthea Bm
Faculty of Medicine, University of Ottawa, Canada.
Department of Family and Community Medicine, University of Toronto, Canada.
Obstet Med. 2022 Jun;15(2):91-98. doi: 10.1177/1753495X211038157.
In this study, we discuss vertical transmission of SARS-CoV-2, and assess various maternal and neonatal outcomes based on the current evidence available. This systematic review using PRISMA guidelines revealed a total of 47 eligible studies describing 1188 SARS-CoV-2 positive pregnant women and 985 neonates for review. Utilizing the 'Shah's Classification System for Maternal-Fetal-Neonatal SARS-CoV-2 Intrauterine Infections' by Shah et al., we found vertical transmission confirmed in 0.3% ( = 3), probable in 0.5% ( = 5), possible in 1.8% ( = 17), unlikely in 80.3% (724) and not infected in 17% ( = 153).
在本研究中,我们讨论了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的垂直传播,并根据现有证据评估了各种孕产妇和新生儿结局。这项使用系统评价和Meta分析的首选报告项目(PRISMA)指南的系统评价共纳入了47项符合条件的研究,涉及1188名SARS-CoV-2阳性孕妇和985名新生儿以供审查。利用沙阿等人的“孕产妇-胎儿-新生儿SARS-CoV-2宫内感染沙阿分类系统”,我们发现确诊垂直传播的比例为0.3%(n = 3),可能垂直传播的比例为0.5%(n = 5),可能存在垂直传播的比例为1.8%(n = 17),垂直传播不太可能发生的比例为80.3%(n = 724),未感染的比例为17%(n = 153)。