Liu Xin, Tang Hong-Yan, Luo Zhi-Cheng
Department of Dermatology,Lanzhou University Second Hospital,Lanzhou 730000,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2020 Apr 28;42(2):247-250. doi: 10.3881/j.issn.1000-503X.11609.
Insulin resistance refers to a pathological condition in which cells fail to respond sufficiently to insulin,leading to impaired glucose uptake and utilization. In recent years,some skin diseases have been found to be associated with metabolic syndrome,and insulin resistance is considered to be the most important pathophysiological feature of the metabolic syndrome. Recent literatures have described the role of insulin resistance in the pathogenesis of these skin diseases. This article elucidates the mechanisms of insulin resistance involved in skin diseases.
胰岛素抵抗是指细胞对胰岛素反应不足的一种病理状态，导致葡萄糖摄取和利用受损。近年来，一些皮肤病被发现与代谢综合征有关，胰岛素抵抗被认为是代谢综合征最重要的病理生理特征。最近的文献描述了胰岛素抵抗在这些皮肤病发病机制中的作用。本文阐明了胰岛素抵抗在皮肤病中的作用机制。
