Mo Shirley, Gupta Sai S, Stroud Anna, Strazdins Erika, Hamizan Aneeza W, Rimmer Janet, Alvarado Raquel, Kalish Larry, Harvey Richard J
Rhinology and Skull Base Research Group, St. Vincent's Centre for Applied Medical Research, University of New South Wales, Sydney, New South Wales, Australia.
Department of Otolaryngology-Head and Neck Surgery, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Laryngoscope. 2021 Feb;131(2):260-267. doi: 10.1002/lary.28682. Epub 2020 May 9.
Nasal peak inspiratory flow (NPIF) is a practical and affordable tool that measures maximum inspiratory flow rate through both nostrils. Although NPIF values for healthy controls and patients appear to differ considerably, a generally expected value for populations with and without nasal obstruction has yet to be established. The aim of this systematic review and meta-analysis was to determine the mean NPIF value in populations with and without nasal obstruction.
Medline (1946-) and Embase (1947-) were searched until July 1, 2017. A search strategy was used to identify studies that reported NPIF values for defined healthy or disease states. All studies providing original data were included. The study population was defined as having either normal nasal breathing or nasal obstruction. A meta-analysis of the mean data was presented in forest plots, and data were presented as mean (95% confidence interval [CI]).
The search yielded 1,526 studies, of which 29 were included. The included studies involved 1,634 subjects with normal nasal breathing and 817 subjects with nasal obstruction. The mean NPIF value for populations with normal nasal breathing was 138.4 (95% CI: 127.9-148.8) L/min. The mean value for populations with nasal obstruction was 97.5 (95% CI: 86.1-108.8) L/min.
Current evidence confirms a difference between mean NPIF values of populations with and without nasal obstruction. The mean value of subjects with no nasal obstruction is 138.4 L/min, and the mean value of nasally obstructed populations is 97.5 L/min. Prospective studies adopting a standardized procedure are required to further assess normative NPIF values. Laryngoscope, 131:260-267, 2021.
鼻吸气峰流量（NPIF）是一种实用且经济的工具，可测量通过双侧鼻孔的最大吸气流量。尽管健康对照者和患者的NPIF值似乎有很大差异，但尚未确定有和没有鼻阻塞人群的一般预期值。本系统评价和荟萃分析的目的是确定有和没有鼻阻塞人群的平均NPIF值。
检索Medline（1946年起）和Embase（1947年起）至2017年7月1日。采用检索策略识别报告特定健康或疾病状态下NPIF值的研究。纳入所有提供原始数据的研究。研究人群定义为具有正常鼻呼吸或鼻阻塞。在森林图中呈现平均数据的荟萃分析，数据以均值（95%置信区间[CI]）表示。
检索共获得1526项研究，其中29项被纳入。纳入的研究涉及1634名鼻呼吸正常的受试者和817名鼻阻塞受试者。鼻呼吸正常人群的平均NPIF值为138.4（95%CI：127.9 - 148.8）L/分钟。鼻阻塞人群的平均值为97.5（95%CI：86.1 - 108.8）L/分钟。
当前证据证实有和没有鼻阻塞人群的平均NPIF值存在差异。无鼻阻塞受试者的平均值为138.4 L/分钟，鼻阻塞人群的平均值为97.5 L/分钟。需要采用标准化程序的前瞻性研究来进一步评估NPIF的标准值。《喉镜》，2021年，131卷：260 - 267页 。
