Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; Harvard-MIT Division of Health Sciences and Technology, Boston, MA 02115, USA.
Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
Cell. 2020 May 28;181(5):1131-1145.e21. doi: 10.1016/j.cell.2020.04.015. Epub 2020 May 7.
There are many unanswered questions about the population history of the Central and South Central Andes, particularly regarding the impact of large-scale societies, such as the Moche, Wari, Tiwanaku, and Inca. We assembled genome-wide data on 89 individuals dating from ∼9,000-500 years ago (BP), with a particular focus on the period of the rise and fall of state societies. Today's genetic structure began to develop by 5,800 BP, followed by bi-directional gene flow between the North and South Highlands, and between the Highlands and Coast. We detect minimal admixture among neighboring groups between ∼2,000-500 BP, although we do detect cosmopolitanism (people of diverse ancestries living side-by-side) in the heartlands of the Tiwanaku and Inca polities. We also highlight cases of long-range mobility connecting the Andes to Argentina and the Northwest Andes to the Amazon Basin. VIDEO ABSTRACT.
关于安第斯中南部的人口历史，仍存在许多未解之谜，特别是在大规模社会（如莫切、瓦里、蒂瓦纳库和印加）的影响方面。我们收集了 89 个人类个体的全基因组数据，这些个体的生存时间约为公元前 9000 年至 500 年，其中特别关注国家社会兴起和衰落的时期。今天的遗传结构始于公元前 5800 年，随后是北高地和南高地之间以及高地和沿海地区之间的双向基因流动。我们在公元前 2000 年至 500 年期间检测到邻近群体之间的混合程度最小，尽管我们确实在蒂瓦纳库和印加政体的中心地区检测到了世界性（不同祖先的人并肩生活）。我们还强调了一些长距离迁移的案例，这些迁移将安第斯山脉与阿根廷以及安第斯山脉西北部与亚马逊盆地连接起来。视频摘要。
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