多发性硬化症中再髓鞘化鉴定的问题与陷阱。
Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis.
机构信息
Wellcome-Medical Research Council Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.
Sorbonne Université, Inserm, CNRS, Institut du Cerveau et de la Moelle Épinière, GH Pitié-Salpêtrière, Paris, France.
出版信息
Cell Stem Cell. 2020 May 7;26(5):617-619. doi: 10.1016/j.stem.2020.03.017.
Regenerative medicines that promote remyelination in multiple sclerosis (MS) are making the transition from laboratory to clinical trials. While animal models provide the experimental flexibility to analyze mechanisms of remyelination, here we discuss the challenges in understanding where and how remyelination occurs in MS.
正在将促进多发性硬化症 (MS) 髓鞘再生的再生医学从实验室过渡到临床试验。虽然动物模型提供了分析髓鞘再生机制的实验灵活性，但在这里我们讨论了理解 MS 中髓鞘再生发生的位置和方式的挑战。
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