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[经内镜治疗膀胱尿道吻合口复发性狭窄后尿道自我扩张对人工尿道括约肌发病率的影响]

[Influence of urethral self-dilatation on the morbidity of the artificial urinary sphincter after endoscopic treatment of recurrent stenosis of the vesicourethral anastomosis].

作者信息

Mutelica L, DeCian M, Tricard T, Severac F, Saussine C

机构信息

Service d'urologie, Nouvel hôpital civil, CHU de Strasbourg, Strasbourg, France.

Service d'urologie, Nouvel hôpital civil, CHU de Strasbourg, Strasbourg, France.

出版信息

Prog Urol. 2020 May;30(6):304-311. doi: 10.1016/j.purol.2020.03.008. Epub 2020 May 5.

DOI:10.1016/j.purol.2020.03.008
PMID:32386679
Abstract

OBJECTIVE

To analyze the morbidity of the practice of daily self-dilatation (SD) in patients undergoing total prostatectomy, who have had artificial urinary sphincter (AUS) for urinary incontinence (UI) and who have had a recurrence of endoscopically treated vesicourethral anastomosis (VUS) stenosis.

MATERIALS AND METHOD

One hundred and thirty-eight patients with SUA for urinary incontinence (UI) fitted between 1998 and 2007 were divided into two groups. Thirty-five patients have had used self-dilatation (SD) for recurrent anastomotic stenosis (SD group) and 103 patients did not perform SD (non-SD group). These two groups were compared for explantation rate (erosion-infection), revision rate (urethral atrophy and mechanical failure) and 2-year functional results. The uni- and multivariate statistical analysis taken into consideration confounding factors such as age and radiotherapy history. The functional assessment was done by the validated IQoL, Ditrovie and MHU tests.

RESULTS

Patients in both groups were comparable except for the importance of urinary incontinence assessed by PAD test and questionnaires. The explantation rate was significantly higher in the "SD" group (28.5% vs 7.77%) and (OR=4.68, 95% CI [1.490-15.257], P=0.006). There was no significant difference between the two groups in the surgical revision rate (32% vs 20%, OR=0.44, P=0.09). The functional results at two years did not show any significant difference.

CONCLUSIONS

The use of self-dilation for recurrence of stenosis of vesicourethral anastomosis after prostatectomy exposes patients fitted with an SUA to a higher explantation rate.

LEVEL OF EVIDENCE

摘要

目的

分析在接受前列腺全切术、因尿失禁植入人工尿道括约肌(AUS)且内镜治疗的膀胱尿道吻合口(VUS)狭窄复发的患者中,日常自我扩张(SD)操作的发生率。

材料与方法

1998年至2007年间因尿失禁植入SUA的138例患者被分为两组。35例患者因吻合口狭窄采用了自我扩张(SD组),103例患者未进行自我扩张(非SD组)。比较两组的取出率(侵蚀-感染)、翻修率(尿道萎缩和机械故障)以及2年功能结果。单因素和多因素统计分析考虑了年龄和放疗史等混杂因素。功能评估通过经过验证的IQoL、Ditrovie和MHU测试进行。

结果

除通过PAD测试和问卷评估的尿失禁严重程度外,两组患者具有可比性。“SD”组的取出率显著更高(28.5%对7.77%),(OR = 4.68,95% CI [1.490 - 15.257],P = 0.006)。两组手术翻修率无显著差异(32%对20%,OR = 0.44,P = 0.09)。两年时的功能结果未显示任何显著差异。

结论

前列腺切除术后膀胱尿道吻合口狭窄复发时使用自我扩张,会使植入SUA的患者取出率更高。

证据水平

3级。

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