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神经轴的钙化假瘤伴难治性癫痫发作:病例报告及文献复习。

Calcifying pseudoneoplasm of the neuroaxis presenting with refractory seizures: Case report and literature review.

机构信息

Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

出版信息

J Clin Neurosci. 2020 Aug;78:439-443. doi: 10.1016/j.jocn.2020.05.001. Epub 2020 May 6.

DOI:10.1016/j.jocn.2020.05.001
PMID:32387256
Abstract

Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare benign lesions that can arise anywhere within the central nervous system. The etiology of these lesions remains unknown and diagnosis is made on pathohistological analysis. We present the case of a 35-year-old male patient with a history of epilepsy since childhood who was evaluated for refractory seizures. MRI revealed a small lesion in the left-posterior temporal lobe suspected to be a cavernoma. A gross total resection of the lesion was achieved via a left temporal craniotomy and pathological analysis revealed CAPNON. At 6 months follow-up, the patient remained neurologically intact and his seizures had ceased.

摘要

中枢神经系统钙化假性肿瘤(CAPNON)是一种罕见的良性病变,可发生于中枢神经系统的任何部位。这些病变的病因尚不清楚,诊断需依靠病理组织学分析。我们报告了 1 例 35 岁男性患者,其自幼患有癫痫,因耐药性癫痫发作而就诊。MRI 显示左颞叶后段有一小病灶,疑似海绵状血管瘤。通过左颞骨开颅术实现了病变的大体全切除,病理分析显示为 CAPNON。6 个月随访时,患者神经功能完整,癫痫发作停止。

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