在秘鲁亚马逊地区流行的登革热血清型 2 病毒的一种新的遗传变异体。
A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon.
机构信息
Department of Biomedical Sciences, Unit of Virology, Institute of Tropical Medicine, Nationalestraat 155, B-2000, Antwerp, Belgium; Unidad de Virología, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, 15102, Lima, Peru.
Department of Biomedical Sciences, Unit of Virology, Institute of Tropical Medicine, Nationalestraat 155, B-2000, Antwerp, Belgium.
出版信息
Int J Infect Dis. 2020 Jul;96:136-138. doi: 10.1016/j.ijid.2020.04.087. Epub 2020 May 6.
We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.
我们对 2018 年秘鲁于里马瓜斯爆发的登革热疫情中采集的样本进行了登革病毒血清型 2（DENV-2-E）包膜基因测序。该毒株属于美洲/亚洲基因型的 2 谱系。我们报告了一种在 DENV2-E 的 III 结构域中具有两个新突变（I379T 和 V484I）的变异株。
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