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迈向丙型肝炎病毒消除的进展:治疗与实施。

Progress Toward Hepatitis C Virus Elimination: Therapy and Implementation.

机构信息

Viral Hepatitis Clinical Research Program, The Kirby Institute, UNSW Sydney, Sydney, Australia.

Viral Hepatitis Clinical Research Program, The Kirby Institute, UNSW Sydney, Sydney, Australia.

出版信息

Gastroenterol Clin North Am. 2020 Jun;49(2):253-277. doi: 10.1016/j.gtc.2020.01.005. Epub 2020 Mar 29.

DOI:10.1016/j.gtc.2020.01.005
PMID:32389362
Abstract

The World Health Organization has called for the elimination of hepatitis C virus (HCV) as a public health threat by 2030. Highly effective direct-acting antiviral agents provide the therapeutic tools required for elimination. In the absence of a vaccine, HCV elimination will require enhanced primary prevention and an increase in the proportions of people diagnosed and treated. Given that globally only 20% of people with chronic HCV are diagnosed, and around 5% have initiated HCV treatment, the task ahead is enormous. But, global public health needs optimism, and countries currently on track for HCV elimination provide a pathway forward.

摘要

世界卫生组织呼吁到 2030 年消除丙型肝炎病毒(HCV)这一公共卫生威胁。高效的直接作用抗病毒药物为消除 HCV 提供了所需的治疗工具。在没有疫苗的情况下,消除 HCV 将需要加强初级预防,并提高诊断和治疗的比例。鉴于全球只有 20%的慢性 HCV 患者得到诊断,且约 5%的患者开始接受 HCV 治疗,未来的任务十分艰巨。但是,全球公共卫生需要乐观精神,目前正在朝着消除 HCV 的方向前进的国家为我们提供了前进的道路。

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