Viral Hepatitis Clinical Research Program, The Kirby Institute, UNSW Sydney, Sydney, Australia.
Viral Hepatitis Clinical Research Program, The Kirby Institute, UNSW Sydney, Sydney, Australia.
Gastroenterol Clin North Am. 2020 Jun;49(2):253-277. doi: 10.1016/j.gtc.2020.01.005. Epub 2020 Mar 29.
The World Health Organization has called for the elimination of hepatitis C virus (HCV) as a public health threat by 2030. Highly effective direct-acting antiviral agents provide the therapeutic tools required for elimination. In the absence of a vaccine, HCV elimination will require enhanced primary prevention and an increase in the proportions of people diagnosed and treated. Given that globally only 20% of people with chronic HCV are diagnosed, and around 5% have initiated HCV treatment, the task ahead is enormous. But, global public health needs optimism, and countries currently on track for HCV elimination provide a pathway forward.
世界卫生组织呼吁到 2030 年消除丙型肝炎病毒(HCV)这一公共卫生威胁。高效的直接作用抗病毒药物为消除 HCV 提供了所需的治疗工具。在没有疫苗的情况下,消除 HCV 将需要加强初级预防,并提高诊断和治疗的比例。鉴于全球只有 20%的慢性 HCV 患者得到诊断,且约 5%的患者开始接受 HCV 治疗,未来的任务十分艰巨。但是,全球公共卫生需要乐观精神,目前正在朝着消除 HCV 的方向前进的国家为我们提供了前进的道路。